Evidence map›Paper›PMID 40665746›Full record

ArticleJournal of cosmetic dermatology2025

Optimizing Post-Acne Scar Treatment: A Pilot Comparative Study of Endo-Radiofrequency Subcision With and Without Platelet-Rich Plasma.

Najmeh Ahramiyanpour, Roxana Kaveh, Elaheh Lotfi, Fatemeh Rastaghi

Abstract readComparative Study
In one paragraph

Article in Journal of cosmetic dermatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Najmeh AhramiyanpourDepartment of Dermatology, Bushehr Faculty of Medicine, Bushehr University of Medical Sciences, Bushehr, Iran.
Roxana KavehGuilan Road Trauma Research Center, Trauma Institute, Guilan University of Medical Sciences, Rasht, Iran.
Elaheh LotfiYoosefabad Skin and Hair Center, Tehran, Iran.
Fatemeh RastaghiDepartment of Dermatology, Afzalipour Hospital, Afzalipour Faculty of Medicine, Kerman University of Medical Sciences, Kerman, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAcne is a common disorder of the pilosebaceous unit, resulting from increased sebum secretion and the colonization of Propionibacterium. Scarring is the most common consequence of acne and can significantly affect patients' quality of life.

methodsPatients with moderate to severe facial acne scars who were referred to the dermatology clinic in 2023 were enrolled. All patients underwent endo-radiofrequency subcision (Endo-RF subcision) on both sides of the face, with platelet-rich plasma (PRP) administered on one side only. Scarring was assessed using quantitative and qualitative measures based on the Goodman and Baron's global scarring grading system.

resultsTen patients (eight females and two males) completed the study. Although qualitative scores improved in both groups, no statistically significant difference was observed. There was no significant correlation in the percentage of recovery between the two study groups (Endo-RF and PRP + Endo-RF) before and after treatment. Evaluations of the quantitative scores for both groups showed considerable improvements in the number of acne scars. A strongly significant correlation was observed in both groups compared to baseline. Although the combination therapy group showed greater improvement in quantitative scar scores from baseline, the difference was not statistically significant.

conclusionBoth Endo-RF subcision and PRP combined with Endo-RF subcision are safe and effective modalities for treating post-acne scars. Although each method can improve acne scars, the combination therapy of Endo-RF with PRP may yield more desirable results.

Indexed as

Acne VulgarisCicatrixPlatelet-Rich PlasmaAdolescentAdultCombined Modality TherapyFaceFemaleHumansMalePilot ProjectsQuality of LifeSeverity of Illness IndexTreatment OutcomeYoung AdultEndo‐RF subcisionplatelet‐rich‐plasmapost‐acne scar

Identifiers

PMID40665746
PMCPMC12264461

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