Evidence map›Paper›PMID 40665705›Full record

ArticleJournal of medicinal chemistry2025

Development and Preclinical Characterization of [

Zhendong Song, Yinlong Li, Kenneth Dahl, Zhenkun Sun, Jiahui Chen, Xin Zhou, Yabiao Gao, Jian Rong, Chunyu Zhao, Katherine Yuan and 9 more

Abstract read
In one paragraph

Article in Journal of medicinal chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Zhendong SongDepartment of Radiology and Imaging Sciences, Emory University, 1364 Clifton Road, Atlanta, Georgia 30322, United States.
Yinlong LiDepartment of Radiology and Imaging Sciences, Emory University, 1364 Clifton Road, Atlanta, Georgia 30322, United States.
Kenneth DahlPET Science Centre, Precision Medicine and Biosamples, Oncology R&D, AstraZeneca, Karolinska Institutet, Stockholm 17176, Sweden.
Zhenkun SunDepartment of Pharmacology and Chemical Biology, Emory University School of Medicine, Atlanta, Georgia 30322, United States.
Jiahui ChenDepartment of Radiology and Imaging Sciences, Emory University, 1364 Clifton Road, Atlanta, Georgia 30322, United States.ORCID 0000-0001-9186-1110
Xin ZhouDepartment of Radiology and Imaging Sciences, Emory University, 1364 Clifton Road, Atlanta, Georgia 30322, United States.
Yabiao GaoDepartment of Radiology and Imaging Sciences, Emory University, 1364 Clifton Road, Atlanta, Georgia 30322, United States.
Jian RongDepartment of Radiology and Imaging Sciences, Emory University, 1364 Clifton Road, Atlanta, Georgia 30322, United States.ORCID 0000-0002-3960-1669
Chunyu ZhaoDepartment of Radiology and Imaging Sciences, Emory University, 1364 Clifton Road, Atlanta, Georgia 30322, United States.
Katherine YuanDepartment of Radiology and Imaging Sciences, Emory University, 1364 Clifton Road, Atlanta, Georgia 30322, United States.
Ahmad F ChaudharyDepartment of Radiology and Imaging Sciences, Emory University, 1364 Clifton Road, Atlanta, Georgia 30322, United States.
Jimmy S PatelDepartment of Radiology and Imaging Sciences, Emory University, 1364 Clifton Road, Atlanta, Georgia 30322, United States.
Thomas L CollierDepartment of Radiology and Imaging Sciences, Emory University, 1364 Clifton Road, Atlanta, Georgia 30322, United States.
Chongzhao RanAthinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, United States.
Kim S MuehlfenzlEarly Chemical Development, Pharmaceutical Sciences, R&D, AstraZeneca Pharmaceuticals, Gothenburg 43183, Sweden.ORCID 0000-0003-3700-0891
Achi HaiderDepartment of Radiology and Imaging Sciences, Emory University, 1364 Clifton Road, Atlanta, Georgia 30322, United States.
Charles S ElmoreEarly Chemical Development, Pharmaceutical Sciences, R&D, AstraZeneca Pharmaceuticals, Gothenburg 43183, Sweden.
Magnus SchouPET Science Centre, Precision Medicine and Biosamples, Oncology R&D, AstraZeneca, Karolinska Institutet, Stockholm 17176, Sweden.ORCID 0000-0002-4314-2418
Steven H LiangDepartment of Radiology and Imaging Sciences, Emory University, 1364 Clifton Road, Atlanta, Georgia 30322, United States.ORCID 0000-0003-1413-6315

Funding

T32 Training Program in Cancer BiologyT32CA275777 · NCI · EMORY UNIVERSITY · PI David Sung-wen Yu · 2023 to 2026
$1.1M
NCI NIH HHS T32 CA275777
6 · The paper itself

Abstract

The histamine subtype 3 receptor (H

Indexed as

Fluorine RadioisotopesPositron-Emission TomographyRadiopharmaceuticalsReceptors, Histamine H3AnimalsBrainHumansMaleMiceRatsStructure-Activity RelationshipTissue DistributionFluorine-18Fluorine RadioisotopesRadiopharmaceuticalsReceptors, Histamine H3

Identifiers

PMID40665705
PMCPMC12362585

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.