ArticleJournal of applied toxicology : JAT2025
Modification of Oxidative Stress Induced by Exposure to Arsenate in Rat Chondrocytes Treated With Chitosan-Glutathione Nanoparticles.
Article in Journal of applied toxicology : JAT, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Modification of Oxidative Stress Induced by Exposure to Arsenate in Rat Chondrocytes Treated With Chitosan-Glutathione Nanoparticles.Journal of applied toxicology : JAT · 2025Article
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Authors and funding
6 authors.
Funding
Abstract
Nanoparticles can modify the signaling pathways related to the toxic effects of xenobiotics and their toxicity by adding compounds that alter the oxidation-reduction state, such as glutathione (GSH). This work aimed to evaluate the antioxidant capacity of chitosan-glutathione nanoparticles (NPs Q-GSH) to modify lipoperoxidation induced by sodium arsenate using a primary culture of rat chondrocytes as a model. NPs Q-GSH were characterized in size (205.4 ± 33.35 nm), zeta potential (25.6 mV), and percentage of GSH (99.97%). To determine whether the toxicity of sodium arsenate was modified, chondrocytes were exposed to two concentrations of nanoparticles (0.08 and 0.64 μM GSH) for 2 h, followed by a 2-h acute exposure to sodium arsenate at a concentration of 1 × 10
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