ReviewAnnals of human genetics2025
Power and Limitations of Inferring Genetic Ancestry.
Review in Annals of human genetics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Pharmacogenomics and genetic ancestry: an opportunity to transform clinical practice in Colombia.Frontiers in pharmacology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
backgroundThe recent emergence of technologies that capture and analyse genetic variation patterns obtained from a person's DNA sample has led to numerous academic and commercial endeavours to infer individuals' ancestries. In theory, a person's genome contains a wealth of readily accessible information regarding their ancestors, despite only some of our ancestors contributing to the DNA we carry. This makes genetic tests an attractive alternative to the painstaking reconstruction of family trees or directly contacting long-lost relations, particularly when, unless there are notable individuals in the tree, historical and genealogical records tend to diminish in frequency with each generation. However, while powerful, there are limits to what genetic data can unearth, as well as important assumptions underlying these analyses.
methodsThis review describes some of the early history and latest advances in techniques and data used to infer ancestry using genetics, highlighting both the power and limitations of current studies.
conclusionWhile genetics is a powerful means of exploring aspects of people's ancestry, a stronger focus on conveying uncertainty will allow both academics and non-academics to avoid the ever-present risks of over-interpretation.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.