Evidence map›Paper›PMID 40665620›Full record

ArticleMedical physics2025

Entry skin dose reduction in an inline MRI-linac using an electron contamination deflector coupled with a helium volume.

Madiha Tai, Jarrad Begg, Elizabeth Patterson, Peter E Metcalfe, Anatoly Rosenfeld, Bradley M Oborn

Abstract read
In one paragraph

Article in Medical physics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Madiha TaiCentre for Medical Radiation Physics, University of Wollongong, Wollongong, New South Wales, Australia.
Jarrad BeggDepartment of Medical Physics, Liverpool and Macarthur Cancer Therapy Centre, Liverpool, New South Wales, Australia.
Elizabeth PattersonCentre for Medical Radiation Physics, University of Wollongong, Wollongong, New South Wales, Australia.
Peter E MetcalfeCentre for Medical Radiation Physics, University of Wollongong, Wollongong, New South Wales, Australia.
Anatoly RosenfeldCentre for Medical Radiation Physics, University of Wollongong, Wollongong, New South Wales, Australia.
Bradley M ObornCentre for Medical Radiation Physics, University of Wollongong, Wollongong, New South Wales, Australia.

Funding

Australian Research Council Discovery DP120100821Federal Government 1132471
6 · The paper itself

Abstract

backgroundA unique feature of inline MRI-linac prototype systems is the changes to entry surface or skin doses. For the high field (1 T) Australian MRI-linac prototype, a strong surface dose increase is observed. This is a by-product of secondary electron contamination being focused down the MRI bore due to the magnetic field being parallel with the x-ray beam direction. It has been anticipated that future clinical treatments will utilize a 2 cm thick water equivalent bolus layer in air above the patient's skin to absorb the electron contamination that causes the large dose hot spot. However, this will reduce the maximum dose rate of the beam and negate the skin dose-sparing effect typical of MV x-ray beams. PURPOSE: To explore through Monte Carlo (MC) modeling and experimental (Exp) measurements, the skin dose changes when employing a small bespoke permanent magnet electron contamination deflector (ECD) in combination with a helium gas volume (HV) located in the MRI bore. The ECD will purge electron contamination from the beam before it reaches the MRI bore, while the HV minimizes the reintroduction of the contamination above the patient.

methods3D magnetic field models of the Australian MRI-linac coupled with and without the ECD were created in COMSOL Multiphysics, and the magnetic field maps were imported into Geant4 MC simulations. The Geant4 simulations included the 6 MV linac, multileaf collimator (MLC), ECD, HV and a 30

resultsThe skin dose hot spot maximum is measured to be 122.5% (2.4

conclusionsThe inclusion of an ECD coupled with a HV in an inline MRI-linac prototype system has significantly reduced the intensity of the skin dose increases. It appears to be superior solution over a generic 2 cm water bolus for all field sizes and also will retain some skin dose-sparing effect. The methods used in this work are expected to be feasible with other inline MRI-linac designs.

Indexed as

ElectronsHeliumMagnetic Resonance ImagingParticle AcceleratorsRadiation DosageSkinHumansMonte Carlo MethodPhantoms, ImagingHeliuminlineMOSkin™MRI‐Linacskin dosimetry

Identifiers

PMID40665620
PMCPMC12264409

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.