Evidence map›Paper›PMID 40665527›Full record

ArticleMedical physics2025

Characterization of silicon carbide diodes as cost-effective active detectors for proton UHDR dosimetry.

Ivan Lopez Paz, Celeste Fleta, Paula Ibáñez, Ángela Henao, Daniel Sanchez-Parcerisa, Adrián Zazpe, Ines Del Monte-Garcia, Consuelo Guardiola

Abstract read
In one paragraph

Article in Medical physics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ivan Lopez PazInstitute of Microelectronics of Barcelona, IMB-CNM (CSIC), Barcelona, Spain.ORCID https://orcid.org/0000-0002-4300-7064
Celeste FletaInstitute of Microelectronics of Barcelona, IMB-CNM (CSIC), Barcelona, Spain.ORCID https://orcid.org/0000-0002-6591-6744
Paula IbáñezGrupo de Física Nuclear & IPARCOS, Universidad Complutense de Madrid, Madrid, Spain.ORCID https://orcid.org/0000-0001-8612-5303
Ángela HenaoInstitute of Microelectronics of Barcelona, IMB-CNM (CSIC), Barcelona, Spain.ORCID https://orcid.org/0009-0005-6396-0708
Daniel Sanchez-ParcerisaGrupo de Física Nuclear & IPARCOS, Universidad Complutense de Madrid, Madrid, Spain.ORCID https://orcid.org/0000-0002-2245-9539
Adrián ZazpeGrupo de Física Nuclear & IPARCOS, Universidad Complutense de Madrid, Madrid, Spain.
Ines Del Monte-GarciaGrupo de Física Nuclear & IPARCOS, Universidad Complutense de Madrid, Madrid, Spain.ORCID https://orcid.org/0009-0000-0496-5107
Consuelo GuardiolaInstitute of Microelectronics of Barcelona, IMB-CNM (CSIC), Barcelona, Spain.ORCID https://orcid.org/0000-0002-0174-7451

Funding

Agencia Estatal de Investigación (Spain) CEX2023-001397-MComunidad de Madrid MV11/22-5Fundación Bancaria Caixa d'Estalvis i Pensions de Barcelona HR23-00718Horizon 2020 Framework Programme 18HLT04Ministerio de Ciencia e Innovación PID2021-123484OB-I00Universidad Complutense de Madrid PR27/21-014
6 · The paper itself

Abstract

backgroundProton therapy allows for better localization of the dose distribution in the tumor. In addition, the FLASH effect can be exploited to reduce the toxicity to healthy tissue by using short-pulsed treatment at ultra-high dose rates (UHDR). Such intense radiation conditions have limited options for active detectors for dosimetry. PURPOSE: Silicon carbide-based diodes are proposed as a cost-effective alternative to diamond detectors for dosimetry in UHDR.

methodsTwo new SiC diodes designed and fabricated at the Institute of Microelectronics of Barcelona (IMB-CNM) were exposed to 20

resultsFirst, the single diode showed a good dose rate linearity. No indication of saturation was observed even at the highest dose per pulse (DPP) of 25 Gy. This was observed even after over-exposure of 52 kGy of 7 MeV protons, although its response lowered to 31% of the initially measured value. Second, the beam profiles observed by the pixelated detector were consistent with those of the reference measurements. Finally, the full width half maximums of the pulses observed by the pixels show good correlation with the pulse width of the beam.

conclusionsThe SiC detectors developed at IMB-CNM were able to withstand and accurately measure the dose under FLASH compatible beam characteristics, even in the case of low-energy protons (7 MeV). The pixelated device showed promising results for a full array monitor for quality assurance, and the capability of time-resolved pulse measurements, the latter after optimization of the electronics.

Indexed as

Carbon Compounds, InorganicProton TherapyRadiometrySemiconductorsSilicon CompoundsCost-Benefit AnalysisCarbon Compounds, Inorganicsilicon carbideSilicon CompoundsdosimeteryFLASH radiotherapysilicon carbide diodesultra high dose rate

Identifiers

PMID40665527
PMCPMC12271001

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.