Evidence map›Paper›PMID 40665443›Full record

ArticleBMC research notes2025

Challenges in assessing self-reported adherence to antiretroviral therapy among individuals living with HIV/AIDS and mental disorders.

Camila Guadeluppe Maciel, Priscilla Arashiro, Lívia Alves da Silva, Ana Isabel do Nascimento, Danilo Dos Santos Conrado, Gabriel Serrano Ramires Koch, João Cesar Pereira da Cunha, Laysa Gomes Osório, Letícia Suemi Arakaki, Lisany Krug Mareto and 11 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC research notes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Camila Guadeluppe MacielSecretaria Municipal de Saúde Pública de Campo Grande, Campo Grande, MS, Brasil.
Priscilla ArashiroSecretaria Municipal de Saúde Pública de Campo Grande, Campo Grande, MS, Brasil.
Lívia Alves da SilvaHospital Universitário Maria Aparecida Pedrossian, Universidade Federal de Mato Grosso do Sul, Campo Grande, MS, Brasil.
Ana Isabel do NascimentoPrograma de Pós-Graduação em Doenças Infecciosas e Parasitárias, Universidade Federal de Mato Grosso do Sul, Campo Grande, MS, Brasil.
Danilo Dos Santos ConradoPrograma de Pós-Graduação em Doenças Infecciosas e Parasitárias, Universidade Federal de Mato Grosso do Sul, Campo Grande, MS, Brasil.
Gabriel Serrano Ramires KochFaculdade de Medicina, Universidade Federal de Mato Grosso do Sul, Campo Grande, MS, Brasil.
João Cesar Pereira da CunhaFaculdade de Medicina, Universidade Federal de Mato Grosso do Sul, Campo Grande, MS, Brasil.
Laysa Gomes OsórioFaculdade de Medicina, Universidade Federal de Mato Grosso do Sul, Campo Grande, MS, Brasil.
Letícia Suemi ArakakiFaculdade de Medicina, Universidade Federal de Mato Grosso do Sul, Campo Grande, MS, Brasil.
Lisany Krug MaretoPrograma de Pós-Graduação em Doenças Infecciosas e Parasitárias, Universidade Federal de Mato Grosso do Sul, Campo Grande, MS, Brasil.
Maria Eduarda de Souza RodriguesFaculdade de Medicina, Universidade Federal de Mato Grosso do Sul, Campo Grande, MS, Brasil.
Micael Viana de AzevedoFaculdade de Medicina, Universidade Federal de Mato Grosso do Sul, Campo Grande, MS, Brasil.
Robson França Gomes E SilvaFaculdade de Medicina, Universidade Federal de Mato Grosso do Sul, Campo Grande, MS, Brasil.
Rodrigo Mayer PucciFaculdade de Medicina, Universidade Federal de Mato Grosso do Sul, Campo Grande, MS, Brasil.
Samara Tessari PiresFaculdade de Medicina, Universidade Federal de Mato Grosso do Sul, Campo Grande, MS, Brasil.
Sara Raquel Pinto BorgesFaculdade de Medicina, Universidade Federal de Mato Grosso do Sul, Campo Grande, MS, Brasil.
Simony Portela do Carmo DrumondPrograma de Pós-Graduação em Doenças Infecciosas e Parasitárias, Universidade Federal de Mato Grosso do Sul, Campo Grande, MS, Brasil.
Márcio José de MedeirosInstituto Politécnico, Universidade Federal do Rio de Janeiro, Macaé, RJ, Brasil.
Maria Elizabeth Araújo AjallaFaculdade de Medicina, Universidade Federal de Mato Grosso do Sul, Campo Grande, MS, Brasil.
Cláudia Du Bocage Santos-PintoFaculdade de Medicina, Universidade Federal de Mato Grosso do Sul, Campo Grande, MS, Brasil.
Everton Falcão de OliveiraPrograma de Pós-Graduação em Doenças Infecciosas e Parasitárias, Universidade Federal de Mato Grosso do Sul, Campo Grande, MS, Brasil. everton.falcao@ufms.br.ORCID http://orcid.org/0000-0002-0074-5278

Funding

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior 001
6 · The paper itself

Abstract

Studies focusing on individuals living with HIV and mental disorders are crucial to inform and enhance care for this inherently vulnerable population group, especially considering that people living with HIV/AIDS (PLHIV) are more likely to develop mental disorders compared to the general population, contributing to lower adherence to antiretroviral therapy (ART). This study cross-sectional study aimed to assess self-reported adherence to antiretroviral therapy among PLHIV and moderate or severe mental disorders in Campo Grande, Mato Grosso do Sul, Brazil. Patient-reported data from PLHIV who received care in at least one of the Psychosocial Care Network facilities of the Brazilian Unified Health System from 2014 to 2018 were collected to assess the adherence to ART. Among the 76 participants eligible, 35 were included in the study. Substance use-related mental disorders were the most prevalent (45.7%), followed by mood disorders (25.7%) and anxiety (11.4%). Most of the participants had a low ART adherence (62.9%), followed by insufficient adherence (22.9%) and good adherence (14.3%). No significant associations were found between the adherence to ART and the study variables. Our findings suggest the importance of assessing adherence based on both direct and indirect measures, as biological markers and self-report.

Indexed as

Acquired Immunodeficiency SyndromeAnti-HIV AgentsHIV InfectionsMedication AdherenceMental DisordersSelf ReportAdultBrazilCross-Sectional StudiesFemaleHumansMaleMiddle AgedAnti-HIV AgentsAntiretroviral therapyMental disordersSelf-reported adherenceSubstance use-related mental disorders

Identifiers

PMID40665443
PMCPMC12265333

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.