Evidence map›Paper›PMID 40665442›Full record

ArticleBMC research notes2025

Neutron capture-enhanced proton beam therapy outside the irradiation field: in vitro experiments.

Shintaro Shiba, Takahiro Shimo, Masashi Yamanaka, Kazuki Matsumoto, Akihiro Yamano, Kazunori Nitta, Makoto Sakai, Tatsuya Ohno, Koichi Tokuuye, Motoko Omura

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC research notes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Shintaro ShibaDepartment of Radiation Oncology, Shonan Kamakura General Hospital, 1370-1, Okamoto, 247-8533, Kamakura, Kanagawa, Japan. shiba4885@yahoo.co.jp.
Takahiro ShimoDepartment of Medical Physics, Shonan Kamakura General Hospital, Kanagawa, Japan.
Masashi YamanakaDepartment of Medical Physics, Shonan Kamakura General Hospital, Kanagawa, Japan.
Kazuki MatsumotoDepartment of Medical Physics, Shonan Kamakura General Hospital, Kanagawa, Japan.
Akihiro YamanoDepartment of Medical Physics, Shonan Kamakura General Hospital, Kanagawa, Japan.
Kazunori NittaDepartment of Medical Physics, Shonan Kamakura General Hospital, Kanagawa, Japan.
Makoto SakaiDepartment of Radiation Oncology, Gunma University Graduate School of Medicine, Gunma, Japan.
Tatsuya OhnoDepartment of Radiation Oncology, Gunma University Graduate School of Medicine, Gunma, Japan.
Koichi TokuuyeDepartment of Radiation Oncology, Shonan Kamakura General Hospital, 1370-1, Okamoto, 247-8533, Kamakura, Kanagawa, Japan.
Motoko OmuraDepartment of Radiation Oncology, Shonan Kamakura General Hospital, 1370-1, Okamoto, 247-8533, Kamakura, Kanagawa, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the cell-killing effects of neutron capture-enhanced particle therapy (NCEPT) outside the proton beam irradiation (PBI) field.

resultsHuman osteosarcoma cells (MG63) were divided into control and NCEPT groups. Four hours before irradiation, the NCEPT group was exposed to

Indexed as

Boron Neutron Capture TherapyOsteosarcomaProton TherapyCell Line, TumorCell SurvivalHumansMonte Carlo MethodBoron neutron capture reactionBoron neutron capture therapyBoronophenylalanineNeutron capture-enhanced proton beam therapyProton beam therapyRadiotherapy

Identifiers

PMID40665442
PMCPMC12265216

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.