ArticleParasites & vectors2025
Characterizing the transmission dynamics of Trypanosoma cruzi in Triatoma sanguisuga collected from dog kennels in southern Texas.
Article in Parasites & vectors, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Who Feeds theMicroorganisms · 2026Article
- Current status and prospects of nanopore sequencing technology in the detection of pathogenic microorganisms.Frontiers in microbiology · 2026Review
- Chagas Disease in the 21st Century: Global Spread, Ecological Shifts, and Research Frontiers.Biology · 2025Review
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundChagas disease, caused by the protozoan Trypanosoma cruzi, remains a significant public health issue in South America, with increasing concern over its potential transmission in the USA. Triatoma sanguisuga, a triatomine vector, is found in Southern states of the USA, including Texas, raising questions about the local transmission dynamics of T. cruzi. This study aims to characterize Trypanosoma cruzi infection in Triatoma sanguisuga collected from dog kennels in Bulverde and Spring Branch, Texas, with a focus on parasite prevalence and load, genotypic diversity, and blood-feeding sources.
methodsA total of 48 T. sanguisuga insects were collected from kennels in Bulverde (N = 37) and Spring Branch (N = 11). DNA extraction was followed by quantitative polymerase chain reaction (qPCR) to detect and quantify T. cruzi, genotyping via Oxford Nanopore Sequencing of the Miniexon gene, and blood-feeding source identification using the 12S rRNA gene was also conducted. Statistical analysis was performed to assess differences in parasitic load among the locations.
resultsOf the 48 insects, 81.1% from Bulverde and 100% from Spring Branch tested positive for T. cruzi. The median parasitic load was log
conclusionsThis study provides insights into T. cruzi transmission dynamics in southern Texas, demonstrating the active role of domestic dogs and wildlife in the local cycle of infection suggesting endemism of T. cruzi in this region. These findings emphasize the need for continued surveillance and vector control measures to mitigate the risk of Chagas disease transmission in the USA.
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