ArticleBMC cardiovascular disorders2025
Global and Chinese perspectives on the growing burden of heart failure: trends, gender, and age-related differences (1990-2021) based on GBD 2021 data.
Article in BMC cardiovascular disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Nursing interventions to enhance self-care in heart failure: a systematic review interpreted through the COM-B model.Systematic reviews · 2026Pooled it
- Glycemic phenotype, age at diabetes diagnosis, and risk of cardiorenal syndrome type 1 in patients hospitalized with acute heart failure.International journal of cardiology. Heart & vasculature · 2026Article
- Metabolic-inflammatory burden predicts mortality in heart failure across population and ICU cohorts.International journal of cardiology. Cardiovascular risk and prevention · 2026Article
- Publication Characteristics and Reporting Quality of GBD-Derived Burden of Disease Studies: A Cross-Sectional Analysis of Lung Cancer.Journal of evidence-based medicine · 2026Article
- Heart Failure Statistics 2025 Update: A Report From the Korean Society of Heart Failure.International journal of heart failure · 2026Article
- Fluid management among outpatients with chronic heart failure: a cross-sectional study.Frontiers in cardiovascular medicine · 2026Article
- Development and validation of a nomogram for predicting hospitalization-associated disability in older patients with acute heart failure.Frontiers in cardiovascular medicine · 2026Article
- Perceived social support and psychological resilience as mediators between social frailty and the frailty of older patients with heart failure: a cross-sectional study.BioPsychoSocial medicine · 2025Article
- Article
- Identification of key genes for heart failure in dilated cardiomyopathy in different populations.Frontiers in genetics · 2025Article
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6 authors.
Funding
Abstract
backgroundHeart failure (HF) is a growing global health issue, contributing to significant disease burden and increased mortality. The Global Burden of Disease (GBD) study offers comprehensive data on HF trends by age, sex, and region.
objectiveThis study aimed to analyze trends in prevalence and years lived with disability (YLDs) of HF in China and globally from 1990 to 2021 based on GBD 2021 data.
methodsA retrospective analysis using GBD 2021 data was conducted, covering HF burden in 204 countries from 1990 to 2021. Data were analyzed using Joinpoint regression and stratified by age and sex.
resultsGlobal HF prevalence increased from 25.43 million in 1990 to 55.50 million in 2021, with an estimated annual percentage change (EAPC) of 2.50%. YLDs rose from 2.42 million to 5.31 million. In China, the EAPC for HF prevalence was 3.18%, surpassing the global rate. Males exhibited higher HF burden than females, and the disease burden rose sharply in those aged 65 and older.
conclusionBoth global and Chinese HF burdens increased from 1990 to 2021, with China experiencing faster growth. Key public health recommendations include improving early screening, promoting lifestyle interventions, enhancing healthcare access, and integrating new therapies for heart failure.
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