Evidence map›Paper›PMID 40665217›Full record

ArticleBMC geriatrics2025

A biopsychosocial approach to improving multidimensional frailty status in community-dwelling older adults: a protocol for a cluster randomized controlled trial.

Jiao Jiao, David Wai-Kwong Man, Sonia Lippke, Holger Hassel, Bjorn Tsz-King Tam, Connie Hoi-Man Chan, Yuen-Ling Ng, Kenneth Ka-Hei Lo

Registry-linked trialAbstract readClinical Trial Protocol
In one paragraph

Article in BMC geriatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06741878 (A Biopsychosocial Approach to Improving Multidimensional Frailty Status in Community-Dwelling Older Adults), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06741878 nanot yet recruitingnot on this map

A Biopsychosocial Approach to Improving Multidimensional Frailty Status in Community-Dwelling Older Adults

TypeinterventionalSponsorHong Kong Baptist UniversityRan2025 to 2026Enrolled308ConditionsFrailty in Older AdultsArmsExercise, Psychosocial, Nutritional
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jiao Jiao *Department of Sports and Health Sciences, Academy of Wellness and Human Development, Faculty of Arts and Social Sciences, Hong Kong Baptist University, Hong Kong, China. jojojiao@hkbu.edu.hk.ORCID http://orcid.org/0000-0002-2705-6157
David Wai-Kwong Man *Tung Wah College, Hong Kong, China.
Sonia LippkeHamburg University of Applied Sciences/Hochschule für Angewandte Wissenschaften Hamburg (HAW Hamburg), Hamburg, Germany.
Holger HasselBerlin Institute for Health and Social Affairs, Berlin, Germany.
Bjorn Tsz-King TamDepartment of Sports and Health Sciences, Academy of Wellness and Human Development, Faculty of Arts and Social Sciences, Hong Kong Baptist University, Hong Kong, China.
Connie Hoi-Man ChanDr. Stephen Hui Research Centre for Physical Recreation and Wellness, Faculty of Arts and Social Sciences, Hong Kong Baptist University, Hong Kong, China.
Yuen-Ling NgDepartment of Sports and Health Sciences, Academy of Wellness and Human Development, Faculty of Arts and Social Sciences, Hong Kong Baptist University, Hong Kong, China.
Kenneth Ka-Hei LoDepartment of Food Science and Nutrition, The Hong Kong Polytechnic University, Hong Kong, China. kenneth.kh.lo@polyu.edu.hk.ORCID http://orcid.org/0000-0003-4624-2737

Funding

General Research Fund from the Research Grants Council, Hong Kong GRF/HKBU12600824
6 · The paper itself

Abstract

backgroundFrailty is a significant clinical syndrome affecting aging populations, leading to increased risks of negative outcomes such as falls, disability, hospitalization, and premature mortality. The concept has evolved from a simplistic view to a complex view that incorporates physical, psychological, cognitive, and social domains. Early intervention is crucial, yet research on the interactions among these domains is limited. This study protocol aims to outline various combinations of biological, psychosocial and nutritional interventions in prefrail older adults to address their effects on frailty status, including physical, psychological, and social functioning, nutritional status, and lifestyle changes over a 9-month intervention and follow-up period.

methodsThis study is a cluster-randomized controlled trial involving N = 308 prefrail older adults aged 60-80 from 32 community elderly centres in Hong Kong. Participants will be randomly selected and classified into four frailty deficit patterns. They will be assigned to one of four intervention strategies: biological/psychosocial/nutritional, biological/nutritional, psychosocial/nutritional, and inactive control. The intervention will focus on improving physical, psychological, and social functioning, nutritional status, and lifestyle changes over the 9-month period. DISCUSSION: This study is expected to provide substantial evidence on the effectiveness of these strategies in enhancing frailty status across bio-psycho-social domains in diverse elderly groups. The findings will have practical implications for healthcare professionals, caregivers, and policymakers, potentially leading to improved care and support for community-dwelling older adults in Hong Kong.

trial registrationThe trial has been registered in ClinicalTrials.gov under U.S. NIH (ID: NCT06741878, date: December 19, 2024).

Indexed as

Frail ElderlyFrailtyIndependent LivingAgedAged, 80 and overFemaleGeriatric AssessmentHong KongHumansMaleMiddle AgedNutritional StatusRandomized Controlled Trials as TopicBiopsychosocial approachExercise trainingIntervention programsMultidimensional frailtyNutrition educationOlder adultsPsychosocial support

Identifiers

PMID40665217
PMCPMC12261824

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.