Evidence map›Paper›PMID 40665214›Full record

SynthesisBMC nephrology2025

Policy strategies to enhance uptake of conservative kidney management in advanced chronic kidney disease: a systematic review and meta-analysis.

Natasha Chawla, Yot Teerawattananon, Natcha Yongphiphatwong, Natanong Thamcharoen, Henny Aryani, Yin May Tun, Dimple Haresh Butani, Rujira Ngam-Prukwanit, Thunyarat Anothaisintawee

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in BMC nephrology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Natasha ChawlaIndependent Researcher, Bangkok, Thailand.
Yot TeerawattananonHealth Intervention and Technology Assessment Program, Ministry of Public Health, Nonthaburi, Thailand.
Natcha YongphiphatwongThailand Development Research Institute, Bangkok, Thailand.
Natanong ThamcharoenCheewabhibaln Palliative Care Center, Nephrology Division, King Chulalongkorn Memorial Hospital, Bangkok, Thailand.
Henny AryaniHealth Intervention and Technology Assessment Program, Ministry of Public Health, Nonthaburi, Thailand.
Yin May TunHealth Intervention and Technology Assessment Program, Ministry of Public Health, Nonthaburi, Thailand.
Dimple Haresh ButaniHealth Intervention and Technology Assessment Program, Ministry of Public Health, Nonthaburi, Thailand.
Rujira Ngam-PrukwanitKantharalak Hospital, Sisaket, Thailand.
Thunyarat AnothaisintaweeDepartment of Clinical Epidemiology and Biostatistics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand. thunyarat.ano@mahidol.ac.th.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundConservative kidney management (CKM) is an established treatment option for patients with advanced chronic kidney disease(CKD) who are not candidates for kidney replacement therapy(KRT). Despite its benefits, CKM uptake remains low. This systematic review aims to evaluate the effectiveness of policy strategies designed to promote CKM uptake in advanced CKD patients.

methodsRelevant studies were identified through searches of Medline, Scopus, and CINAHL databases since 2000 through 24 July 2024. Observational studies or randomized controlled trials that assessed the efficacy of interventions aiming to increase CKM utilization or preference in patients with chronic kidney disease were eligible for this study. Pairwise meta-analysis using the inverse variance or DerSimonion and Laird method, was applied to estimate the efficacy of interventions across studies.

resultsSeven studies were included in this systematic review. Education and training interventions which provided knowledge about CKM to patients and their families, did not significantly increased preference for CKM among CKD patients, compared to no intervention with a pooled OR of 1.05 (95% CI: 0.62-1.76; I

conclusionOur findings suggest that educating patients and their families about CKM did not result in a statistically significant increase in CKM preference compared to no intervention. In contrast, interventions aimed at reforming healthcare services by implementing prognostication assessments into clinical practice might significantly increase CKM utilization. However, these conclusions are based on a limited number of observational studies, highlighting the need for further research to validate the effectiveness of these interventions.

Indexed as

Conservative TreatmentHealth PolicyRenal Insufficiency, ChronicHumansPatient Education as TopicPatient PreferenceChronic kidney diseaseConservative kidney managementMeta-analysisPolicy interventionSystematic review

Identifiers

PMID40665214
PMCPMC12261656

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.