Evidence map›Paper›PMID 40665130›Full record

ReviewDiabetologia2025

Societal and biological approaches to diabetes prevention and care for Inuit populations: a narrative review.

Helene Nielsen, Fannie Lajeunesse-Trempe, Ai-Ling Lin, Maja H Nielsen, Bodil Hoffmeyer, Trine L J Larsen, Pierre Ayotte, Meera L Narayanan, Anne C B Thuesen, Torben Hansen and 3 more

Abstract readReview
PubMed Publisher
In one paragraph

Review in Diabetologia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Helene NielsenSteno Diabetes Center Greenland, Nuuk, Greenland. hieh@peqqik.gl.ORCID http://orcid.org/0000-0002-8753-3816
Fannie Lajeunesse-TrempeInstitut Universitaire de Cardiologie et de Pneumologie de Québec, Université Laval, Québec, QC, Canada.ORCID http://orcid.org/0009-0002-4036-7854
Ai-Ling LinAlaska Native Tribal Health Consortium Diabetes Program, Alaska Native Tribal Health Consortium, Anchorage, AK, USA.
Maja H NielsenSteno Diabetes Center Greenland, Nuuk, Greenland.ORCID http://orcid.org/0000-0003-1373-7661
Bodil HoffmeyerSteno Diabetes Center Greenland, Nuuk, Greenland.ORCID http://orcid.org/0000-0003-2104-1920
Trine L J LarsenSteno Diabetes Center Greenland, Nuuk, Greenland.ORCID http://orcid.org/0000-0001-5070-4231
Pierre AyotteAxe Santé des Populations et Pratiques Optimales en Santé, Centre de Recherche du CHU de Québec-Université Laval, Québec, QC, Canada.ORCID http://orcid.org/0000-0003-1970-7252
Meera L NarayananAlaska Native Tribal Health Consortium Diabetes Program, Alaska Native Tribal Health Consortium, Anchorage, AK, USA.
Anne C B ThuesenNovo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.ORCID http://orcid.org/0000-0002-8639-9117
Torben HansenNovo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.ORCID http://orcid.org/0000-0001-8748-3831
Michael L PedersenSteno Diabetes Center Greenland, Nuuk, Greenland.ORCID http://orcid.org/0000-0001-8059-9188
Marit E JørgensenSteno Diabetes Center Greenland, Nuuk, Greenland.ORCID http://orcid.org/0000-0001-8356-5565
Stine BybergSteno Diabetes Center Greenland, Nuuk, Greenland.ORCID http://orcid.org/0000-0002-3626-3609

Funding

the Novo Nordisk Foundation NNF20SA0064190the Novo Nordisk Foundation NNF20SA0064340the Novo Nordisk Foundation NNF23SA0084103
6 · The paper itself

Abstract

The Inuit populations that inhabit the Arctic regions have adapted to survive in extreme conditions. However, recent societal changes and colonisation have led to rapid shifts in diet and physical activity, increasing the burden of chronic diseases, especially diabetes, in these regions. In addition, modern-day Inuit face significant challenges in accessing diabetes care and prevention and awareness programmes because of geographical isolation and fragmented healthcare services. This narrative review describes diabetes epidemiology in Inuit populations living in Canada, Alaska and Greenland and their genetic architecture, as well as the organisation of healthcare related to diabetes and interventions aimed at creating awareness and preventing the onset and complications of diabetes in these regions. Despite their shared genetic architecture, differences are observed across Inuit populations in Canada, Alaska and Greenland in diabetes prevalence and healthcare interventions, and especially in the organisation of diabetes healthcare. This narrative review highlights the importance of culturally sensitive healthcare interventions and comprehensive research and data collection that address the specific health needs of the Inuit. Integrating traditional knowledge with modern medical practices is essential for the development of effective, sustainable strategies for diabetes prevention and care for the Inuit living in the circumpolar Arctic regions.

Indexed as

Diabetes MellitusInuitAlaskaArctic RegionsCanadaGreenlandHumansArcticCulturally sensitive interventionsDiabetesEquity, diversity and inclusionGenetics of diabetesInuitReview

Identifiers

PMID40665130

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.