ArticleScientific reports2025
Global burden of cardiovascular disease due to low physical activity, 1990-2021.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Effectiveness of mHealth Interventions on Physical Activity and Sedentary Behavior Among Office Workers: A Systematic Review and Meta-analysis.Journal of occupational rehabilitation · 2026Pooled it
- Comparative burden and projections of chewing tobacco-attributable lip/oral cavity and esophageal cancers: global and China-specific trends, 2000-2036.Annals of medicine · 2026Article
- Global and regional burden of cardiovascular diseases due to low physical activity from 1990 to 2021 and projections to 2045: a joinpoint regression and age-period-cohort analysis based on GBD 2021.Internal and emergency medicine · 2026Article
- Workplace Interventions to Improve Physical Activity, Reduce Sedentary Behavior, and Promote Healthy Diet Among Employees in Low- and Middle- Income Countries: A Systematic Review.Research square · 2026Article
- Biopsychosocial risk factors for Alzheimer's disease and related dementias in UK immigrants from the Middle East and North Africa (MENA).medRxiv : the preprint server for health sciences · 2026Article
- Predictors of exercise participation among Saudi adults attending primary healthcare centers in Riyadh.Scientific reports · 2026Article
- The association of self-rated health with physical activity and demographic factors: a study in primary care from Northwest of Iran.BMC primary care · 2025Article
- An explainable deep learning framework for trustworthy arrhythmia detection from ECG signals.Scientific reports · 2025Article
- Global and regional burden of kidney cancer from 1990 to 2021: analysis and future predictions based on global burden of disease study.BMC cancer · 2025Article
- Rethinking the Diabetes-Cardiovascular Disease Continuum: Toward Integrated Care.Journal of clinical medicine · 2025Article
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We aimed to clarify the distribution of the spatiotemporal burden of Low physical activity (LPA)-related cardiovascular disease (CVD) at the global, regional, and national levels from 1990 to 2021. We systematically extracted Global Burden of Disease Study (GBD) 2021 data on CVD burden attributable to LPA from 1990 to 2021, stratified by Socio-demographic Index (SDI) quintiles and 21 GBD geographical regions. Three complementary metrics were employed: (1) Age-standardized death rate (ASDR) and (2) Disability-Adjusted Life Year (DALY) rate provided cross-sectional burden estimates, while (3) Estimated Annual Percentage Change (EAPC) quantified temporal trends in ASDR/DALY rates. The EAPC-derived trend patterns were further analyzed in conjunction with SDI levels and regional variations to identify disparities in physical inactivity-related CVD burden. The age-standardized DALY rate (EAPC = -1.30) and ASDR (EAPC = -1.41) for CVD attributable to LPA showed a decreasing trend from 1990 to 2021. The highest age-standardized DALY rate and ASDR per 100,000 population across all five SDI regions were observed in the Low-middle SDI region (111.53; 5.67). Among the 21 geographic regions and 204 countries, the highest age-standardized DALY rate and ASDR per 100,000 population for CVD attributable to LPA in 2021 were both reported in North Africa and the Middle East (211.62; 10.50), with Sudan having the highest rates (616.58; 24.56). The largest increase in the age-standardized DALY rate from 1990 to 2021 was observed in Southeast Asia (EAPC = 0.19), while the most substantial increase in ASDR was noted in Southern sub-Saharan Africa (EAPC = 0.44). Both the age- standardized DALY rate and ASDR increased the most in Lesotho (EAPC = 2.30; EAPC = 2.39). Although the global burden of CVD attributable to LPA has decreased from 1990 to 2021, the burden remains significant in low- and middle-income countries.
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