ArticleJournal of ultrasound2025
Accuracy of shear wave elastography in diagnosing axillary lymph node metastasis in patients with suspicious axillary lymph nodes: development of a predictive nomogram.
Article in Journal of ultrasound, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Lymph Node Assessment with Multiparametric Ultrasound: Normal Values, Morphologic Patterns, and Diagnostic Algorithms.Cancers · 2026Article
- Toward a more comprehensive approach to axillary evaluation in breast cancer using shear wave elastography.Journal of ultrasound · 2026Article
- Integrin-Mediated Mechanosensing of Modeled Lymph Node Microenvironment Promotes T Cell Activation via Nuclear Deformation.Research (Washington, D.C.) · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThis study aimed to evaluate shear wave elastography [SWE] for predicting axillary lymph node metastasis in breast cancer patients.
methodsThirty-nine patients with suspicious axillary lymph nodes (BI-RADS ≥ 4 and abnormal B-mode ultrasound features) underwent B-mode ultrasound, strain elastography, and shear wave elastography (SWE) prior to ultrasound-guided core needle biopsy. Two experienced radiologists independently assessed lymph node appearance, cortical thickness, vascularity, as well as shear wave and strain elastography using the Siemens ACUSON Sequoia system. Statistical analysis compared imaging parameters between benign and malignant nodes using the Wilcoxon rank-sum test. Diagnostic performance was evaluated using receiver operating characteristic (ROC) curves. A predictive nomogram incorporating B-mode, strain elastography, and SWE findings was developed to improve diagnostic accuracy.
resultsMalignant nodes showed significantly higher stiffness and velocity [p < 0.05]. Cut points for diagnostic accuracy were determined by using the Youden index. Combining B-Mode and elastography improved sensitivity and specificity. A predictive nomogram incorporating SWE, strain elastography, and B-Mode appearance achieved high diagnostic efficacy [sensitivity = 0.96, specificity = 0.77, PPV = 0.89, NPV = 0.91].
conclusionsSWE demonstrates potential as a non-invasive tool for axillary nodal assessment in breast cancer patients. It effectively distinguishes between benign and malignant axillary lymph nodes, offering promise for optimizing management. The predictive nomogram, incorporating SWE, strain elastography, and B-Mode appearance, provides a practical tool for pre-operative decision-making, enhancing the diagnostic process and potentially improving the management of breast cancer patients.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.