Evidence map›Paper›PMID 40665080›Full record

ArticleSleep & breathing = Schlaf & Atmung2025

Patterns and stability of long-term adherence in continuous positive airway pressure therapy for obstructive sleep apnea: a cohort study.

Karin Jeppesen, Asbjørn Kørvel-Hanquist, Donna Lykke Wolff, Sofie Ronja Petersen, Preben Homøe, Eva Kirkegaard Kiær, Poul Jørgen Jennum, Helene Skjøt-Arkil

Abstract readMulticenter Study
In one paragraph

Article in Sleep & breathing = Schlaf & Atmung, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Review
  6. Review
  7. Should weight loss be the first-line treatment for obstructive sleep apnoea? A pro-con debate.European respiratory review : an official journal of the European Respiratory Society · 2026
    Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Karin JeppesenDepartment of Ear, Nose and Throat Surgery, University Hospital of Southern Denmark, Sønderborg, Denmark. Karin.jeppesen@rsyd.dk.ORCID 0000-0002-1692-9901
Asbjørn Kørvel-HanquistDepartment of Otorhinolaryngology and Maxillofacial Surgery, Zealand University Hospital, Køge, Denmark.ORCID 0000-0002-6645-1926
Donna Lykke WolffDepartment of Regional Health Research, University of Southern Denmark, Odense, Denmark.ORCID 0000-0002-9131-8991
Sofie Ronja PetersenDepartment of Clinical Research, University Hospital of Southern Denmark, Aabenraa, Denmark.ORCID 0000-0001-6177-8930
Preben HomøeDepartment of Otorhinolaryngology and Maxillofacial Surgery, Zealand University Hospital, Køge, Denmark.ORCID 0000-0003-2877-3518
Eva Kirkegaard KiærDepartment of Otorhinolaryngology, Head and Neck Surgery, and Audiology, Copenhagen University Hospital, Copenhagen, Denmark.ORCID 0000-0002-4922-0384
Poul Jørgen JennumDepartment of Clinical Medicine, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0001-6986-5254
Helene Skjøt-ArkilDepartment of Regional Health Research, University of Southern Denmark, Odense, Denmark.ORCID 0000-0002-2236-6375

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose• Despite being the gold standard for treating obstructive sleep apnea (OSA), continuous positive airway pressure (CPAP) therapy faces a persistent challenge: patient adherence. This study aimed to investigate long-term adherence and stabilisation patterns after initiating CPAP therapy.

methods• We conducted a multicenter cohort study using tele-monitored CPAP data from adult patients treated for at least 24 months at two Danish sleep clinics. These data were combined with local hospital administrative data and national registry data.

results• The study included data from 1,907 OSA patients who had initiated CPAP. The median age was 55 years (SD 12.5), and 26% were females. After long-term CPAP therapy, 45% of the OSA patients had achieved high adherence to CPAP, while 39% were CPAP non-adherent, and 16% of the patients were in the low-adherent group. The probability of high adherence after two years was 79% if the patient achieved high adherence within the first month. All groups showed stability within the first three months after CPAP initiation, particularly for the CPAP non-adherent patients and the patients with high adherence.

conclusion• We found that less than half of the OSA patients achieved high adherence to CPAP therapy 24 months after CPAP initiation. Patients who achieved high adherence within the first month were more likely to maintain it.

Indexed as

Continuous Positive Airway PressurePatient ComplianceSleep Apnea, ObstructiveAdultAgedCohort StudiesDenmarkFemaleFollow-Up StudiesHumansMaleMiddle AgedTelemedicineAdherenceContinuous positive airway pressure (CPAP)Obstructive sleep apnea (OSA)Sleep clinicVirtual data

Identifiers

PMID40665080
PMCPMC12263751

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.