Evidence map›Paper›PMID 40664958›Full record

ArticleScientific reports2025

Oryzalin-Induced polyploidy enhances natural metabolite accumulation and functional bioactivities in novel Callisia fragrans genotype.

Neha Gupta, Soham Bhattacharya, Jana Žiarovská, Adrish Dutta, Veronika Fialková, Silvia Farkasová, Anna Mascellani Bergo, Jaroslav Havlik, Jan Tauchen, Pavel Novy and 3 more

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Neha Gupta *Department of Crop Sciences and Agroforestry, Faculty of Tropical AgriSciences, Czech University of Life Sciences Prague, Kamýcká 129, Prague 6, Suchdol, 16500, Czech Republic.
Soham Bhattacharya *Department of Agroecology and Crop Production, Faculty of Agrobiology, Food and Natural Resources, Czech University of Life Sciences Prague, Kamýcká 129, Prague 6, Suchdol, 16500, Czech Republic.
Jana ŽiarovskáInstitute of Plant and Environmental Sciences, Faculty of Agrobiology and Food Resources, Slovak University of Agriculture in Nitra, Tr. A. Hlinku 2, Nitra, Slovak Republic.
Adrish DuttaDepartment of Crop Sciences and Agroforestry, Faculty of Tropical AgriSciences, Czech University of Life Sciences Prague, Kamýcká 129, Prague 6, Suchdol, 16500, Czech Republic.
Veronika FialkováAgroBioTech Research Centre, Slovak University of Agriculture in Nitra, Trieda Andreja Hlinku 2, Nitra, 949 76, Slovakia.
Silvia FarkasováAgroBioTech Research Centre, Slovak University of Agriculture in Nitra, Trieda Andreja Hlinku 2, Nitra, 949 76, Slovakia.
Anna Mascellani BergoDepartment of Food Science, Faculty of Agrobiology, Food and Natural Resources, Czech University of Life Sciences Prague, Kamýcká 129, Prague 6, Suchdol, 16500, Czech Republic.
Jaroslav HavlikDepartment of Food Science, Faculty of Agrobiology, Food and Natural Resources, Czech University of Life Sciences Prague, Kamýcká 129, Prague 6, Suchdol, 16500, Czech Republic.
Jan TauchenDepartment of Food Science, Faculty of Agrobiology, Food and Natural Resources, Czech University of Life Sciences Prague, Kamýcká 129, Prague 6, Suchdol, 16500, Czech Republic.
Pavel NovyDepartment of Food Science, Faculty of Agrobiology, Food and Natural Resources, Czech University of Life Sciences Prague, Kamýcká 129, Prague 6, Suchdol, 16500, Czech Republic.
Klára UrbanováDepartment of Sustainable Technologies, Faculty of Tropical AgriSciences, Czech University of Life Sciences Prague, Prague, Czech Republic.
Luigi MilellaDepartment of Science, University of Basilicata, Via Dell'Ateneo Lucano 10, Potenza, 85100, Italy.
Eloy Fernández-CusimamaniDepartment of Crop Sciences and Agroforestry, Faculty of Tropical AgriSciences, Czech University of Life Sciences Prague, Kamýcká 129, Prague 6, Suchdol, 16500, Czech Republic. eloy@ftz.czu.cz.

Funding

Internal Grant Agency of FTA 20243106METROFOOD-CZ LM2023064; LM2018100National Agency of Agricultural Research of the Ministry of Agriculture of the Czech Republic QK1910209
6 · The paper itself

Abstract

The reorientation of Callisia fragrans (Lindl.) Woodson, from therapeutic to ornamental use, exemplifies a broader domestication trend, favoring aesthetics over medicinal properties. Renewed phytomedicinal interest and the rise of plant extract markets drive demand for organic, sustainable consumer products, heightening the competition for superior cultivars. Synthetic polyploidization using oryzalin was conducted to obtain high-quality cultivars of C. fragrans, facilitating enhanced phenotypic and biological traits without genetic modification. This study aimed to explore the metabolic spectrum and biological activities of oryzalin-induced polyploid C. fragrans for its advanced medicinal application. Flow cytometric analysis confirmed the ploidy level of the plants. Consequently, GC-FID and

Indexed as

Plant ExtractsPolyploidyAntioxidantsCyclooxygenase 1Cyclooxygenase 2GenotypeHumansAntioxidantsCyclooxygenase 1Cyclooxygenase 2Plant ExtractsAnti-inflammatory activityAntioxidant activityGC-FIDNMRPolyploidizationSkin infection

Identifiers

PMID40664958
PMCPMC12263847

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.