Evidence map›Paper›PMID 40664874›Full record

ArticleScientific reports2025

Inhibiting astrocyte calcium dynamics terminates status epilepticus via wireless septal stimulation.

Chunxiao Tian, Qiuying Xue, Tongrui Wu, Jingyu Zhao, Chao Tian, Yuxuan Zhu, Hualin He, Aili Liu, Lei Dong, Yu Zheng and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Chunxiao Tian *School of Biomedical Engineering, Tianjin Medical University, Tianjin, China.
Qiuying Xue *School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China.
Tongrui Wu *School of Biomedical Engineering, Tianjin Medical University, Tianjin, China.
Jingyu ZhaoSchool of Biomedical Engineering, Tianjin Medical University, Tianjin, China.
Chao TianDepartment of Anesthesiology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
Yuxuan ZhuSchool of Basic Medical Sciences, Tianjin Medical University, Tianjin, China.
Hualin HeSchool of Basic Medical Sciences, Tianjin Medical University, Tianjin, China.
Aili LiuSchool of Basic Medical Sciences, Tianjin Medical University, Tianjin, China.
Lei DongSchool of Life Sciences, Tiangong University, Tianjin, China.
Yu ZhengSchool of Life Sciences, Tiangong University, Tianjin, China.
Hui ShenSchool of Basic Medical Sciences, Tianjin Medical University, Tianjin, China. shenhui@tmu.edu.cn.

Funding

the Joint Funds for the STI2030-Major Projects Grant No.2021ZD0202900the National Natural Science Foundation of China Grant Nos. 62027812the National Science Foundation of Tianjin 23JCZDJC00440
6 · The paper itself

Abstract

Status epilepticus (SE) is an acute medical emergency with unclear cellular and circuit mechanisms, and it is imperative to develop anti-SE strategies. Here, we observe distinct astrocytic Ca

Indexed as

AstrocytesCalciumStatus EpilepticusAnimalsDeep Brain StimulationDisease Models, AnimalGABAergic NeuronsMalePilocarpineRatsRats, Sprague-DawleySeizuresCalciumPilocarpineAstrocytesCa2+ activityFocal seizureGeneralized seizureWireless electrical stimulation

Identifiers

PMID40664874
PMCPMC12263835

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.