Evidence map›Paper›PMID 40664825›Full record

ArticleNPJ Parkinson's disease2025

Effects of specialised physiotherapy on mortality in Parkinson's disease: a prospective observational study.

Jan H L Ypinga, Lieke H H M Boonen, Marten Munneke, Patrick P T Jeurissen, Yoav Ben-Shlomo, Bastiaan R Bloem, Nienke M de Vries, Sirwan K L Darweesh

Abstract read
In one paragraph

Article in NPJ Parkinson's disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jan H L YpingaRadboud University Medical Centre; Donders Institute for Brain, Cognition and Behaviour; Department of Neurology, Nijmegen, The Netherlands. jan.ypinga@radboudumc.nl.
Lieke H H M BoonenErasmus School of Health Policy & Management, Erasmus University Rotterdam, Rotterdam, the Netherlands.
Marten MunnekeRadboud University Medical Centre; Donders Institute for Brain, Cognition and Behaviour; Department of Neurology, Nijmegen, The Netherlands.
Patrick P T JeurissenRadboud University Medical Center, Radboud Institute for Health Sciences, IQ Healthcare, Nijmegen, The Netherlands.
Yoav Ben-ShlomoDepartment of Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
Bastiaan R BloemRadboud University Medical Centre; Donders Institute for Brain, Cognition and Behaviour; Department of Neurology, Nijmegen, The Netherlands.
Nienke M de VriesRadboud University Medical Centre; Donders Institute for Brain, Cognition and Behaviour; Department of Neurology, Nijmegen, The Netherlands.
Sirwan K L DarweeshRadboud University Medical Centre; Donders Institute for Brain, Cognition and Behaviour; Department of Neurology, Nijmegen, The Netherlands.

Funding

Wellcome Trust
6 · The paper itself

Abstract

Previous studies found that specialised allied health interventions in people with Parkinson's disease (PD) are associated with fewer complications and lower costs, as compared to usual care. Here we studied the association between specialised physiotherapy with mortality risk in a real world setting. We performed a retrospective cohort study using a health insurance claims database capturing persons with PD in the Netherlands with a follow-up of ten years. In persons treated for PD-related indications (n = 37,729), specialised physiotherapy was associated with a lower mortality rate ratio (0.89; 95% CI [0.86; 0.92]; P < 0.0001) than usual care physiotherapy. The association was attenuated in persons with PD with worse mental health (1.00), higher healthcare costs (0.91) in the year prior to enrolment and for females (0.91). These findings suggest that specialised physiotherapy for PD-related indications may delay death in persons with PD, although we cannot exclude the possibility of residual confounding.

Identifiers

PMID40664825
PMCPMC12264191

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.