Evidence map›Paper›PMID 40664807›Full record

ArticleScientific reports2025

Sensitive detection of dengue serotype-4 on lignin-derived graphene nanofibre and manganese oxide composite by DNA-sensing.

Sivainesh Devi Remesh, Saravanan Karuppanan, Veeradasan Perumal, Subash C B Gopinath, Mark Ovinis, Pandian Bothi Raja, Natarajan Arumugam, Raju Suresh Kumar

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In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sivainesh Devi RemeshCentre of Innovative Nanostructures and Nanodevices (COINN), Universiti Teknologi PETRONAS, 32610, Seri Iskandar, Perak Darul Ridzuan, Malaysia.
Saravanan KaruppananDepartment of Mechanical Engineering, Universiti Teknologi PETRONAS, 32610, Seri Iskandar, Perak Darul Ridzuan, Malaysia. saravanan_karuppanan@utp.edu.my.
Veeradasan PerumalCentre of Innovative Nanostructures and Nanodevices (COINN), Universiti Teknologi PETRONAS, 32610, Seri Iskandar, Perak Darul Ridzuan, Malaysia. veeradasan.perumal@utp.edu.my.
Subash C B GopinathCenter for Global Health Research, Saveetha Medical College & Hospital, Saveetha Institute of Medical and Technical Sciences, Chennai, 602105, Tamil Nadu, India.
Mark OvinisCollege of Engineering, Faculty of Computing, Engineering and the Built Environment, Birmingham City University, Birmingham, B4 7BD, UK.
Pandian Bothi RajaSchool of Chemical Sciences, Universiti Sains Malaysia, Gelugor, Penang, 11800, Malaysia.
Natarajan ArumugamDepartment of Chemistry, College of Science, King Saud University, P.O. Box 2455, Riyadh, 11451, Saudi Arabia.
Raju Suresh KumarDepartment of Chemistry, College of Science, King Saud University, P.O. Box 2455, Riyadh, 11451, Saudi Arabia.

Funding

King Saud University, Riyadh, Saudi Arabia RSP2024R143Yayasan UTP 015LC0-443
6 · The paper itself

Abstract

This research addresses the critical challenge of achieving precise DNA detection in complex biological samples by developing a novel, eco-friendly dengue virus serotype 4 biosensor. Utilizing laser-scribed graphene nanofibers derived from sustainable oil palm lignin, a cost-effective alternative to conventional graphene, the biosensor leverages the material's high surface area and conductivity for enhanced DNA immobilization and signal transduction. While lignin-derived graphene's heterogeneous structure poses challenges to electrochemical performance, this study overcomes these limitations by synthesizing laser scribed-graphene nanofibres (LSGNF) decorated with manganese oxide nanoparticles. Field-emission scanning electron microscopy images revealed a highly advantageous three-dimensional, interconnected network of thin, wrinkled sheets forming a porous scaffold, providing efficient electron transport and enhanced molecular interaction. Transmission electron microscopy further confirmed the successful integration of Mn

Indexed as

Biosensing TechniquesDengueDengue VirusDNA, ViralGraphiteLigninManganese CompoundsNanofibersOxidesNanocompositesSpectroscopy, Fourier Transform InfraredDNA, ViralGraphiteLigninManganese Compoundsmanganese oxideOxidesDengue biosensorLaser-scribed grapheneManganese oxide nanoparticleNanomaterial

Identifiers

PMID40664807
PMCPMC12263869

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.