Evidence map›Paper›PMID 40664749›Full record

ArticleScientific reports2025

Green synthesis of silver nanoparticles from plant Astragalus fasciculifolius Bioss and evaluating cytotoxic effects on MCF7 human breast cancer cells.

Fatemeh Nosrati, Baratali Fakheri, Habib Ghaznavi, Nafiseh Mahdinezhad, Roghayeh Sheervalilou, Bahman Fazeli-Nasab

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Fatemeh NosratiDepartment of Plant Breeding and Biotechnology, Faculty of Agriculture, University of Zabol, Zabol, Iran.
Baratali FakheriDepartment of Plant Breeding and Biotechnology, Faculty of Agriculture, University of Zabol, Zabol, Iran. Fakheri@uoz.ac.ir.
Habib GhaznaviPharmacology Research Center, Zahedan University of Medical Sciences, Zahedan, Iran.
Nafiseh MahdinezhadDepartment of Plant Breeding and Biotechnology, Faculty of Agriculture, University of Zabol, Zabol, Iran.
Roghayeh SheervalilouPharmacology Research Center, Zahedan University of Medical Sciences, Zahedan, Iran.
Bahman Fazeli-NasabDepartment of Agronomy and Plant Breeding, Agriculture Institute, Research Institute of Zabol, Zabol, Iran. bfazelinasab@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Astragalus fasciculifolius Bioss, commonly known as Anzaroot, is a medicinal plant from the Fabaceae family, recognized for its therapeutic properties due to its rich composition of saponins, flavonoids, and polysaccharides. These compounds have been shown to effectively treat heart diseases and inhibit cancer cell growth while also alleviating chemotherapy side effects. Recent research has focused on the green synthesis of silver nanoparticles (AgNPs) from Anzaroot, exploring their potential cytotoxic effects against MCF-7 human breast cancer cells. This study aims to bridge traditional herbal medicine and modern nanotechnology by evaluating the anticancer properties of AgNPs derived from this lesser-explored plant. This study was aimed to assess the cytotoxic effect of Anzaroot and green synthesized AgNPs using aqueous extract of Anzaroot on the MCF-7 cell line. To optimization of AgNPs synthesis, different parameters were evaluated including Anzaroot aqueous extract volumes (1, 2, 3 and 4 ml), silver nitrate solution (AgNO

Indexed as

Astragalus PlantBreast NeoplasmsGreen Chemistry TechnologyMetal NanoparticlesPlant ExtractsSilverCell SurvivalFemaleHumansMCF-7 CellsPlant ExtractsSilverAnzaroot-silver nanoparticles (Anz@AgNPs)Astragalus fasciculifolius (Anzaroot)Breast cancerCytotoxicitySilver nanoparticles (AgNPs)

Identifiers

PMID40664749
PMCPMC12264097

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.