Evidence map›Paper›PMID 40664512›Full record

ArticleeNeuro2025

Reinforced Odor Representations in the Anterior Olfactory Nucleus Can Serve as Memory Traces for Conspecifics.

Christiane Linster, David Wolf, Wolfgang Kelsch

Abstract read
In one paragraph

Article in eNeuro, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Christiane LinsterDepartment of Neurobiology and Behavior, Cornell University, Ithaca, New York 14850 cl243@cornell.edu.ORCID https://orcid.org/0000-0003-1444-7295
David WolfDepartment of Psychiatry and Psychotherapy, University Medical Center, Johannes Gutenberg University, Mainz 55131, Germany.
Wolfgang KelschDepartment of Psychiatry and Psychotherapy, University Medical Center, Johannes Gutenberg University, Mainz 55131, Germany.ORCID https://orcid.org/0000-0002-3470-8125

Funding

Role of anterior olfactory nucleus for multi-sensory integration in the olfactory systemR01DC019124 · NIDCD · CORNELL UNIVERSITY · PI CLELAND, THOMAS A, LINSTER, CHRISTIANE · 2021 to 2025
$3.2M
NIDCD NIH HHS R01 DC019124
6 · The paper itself

Abstract

Recognition of conspecific individuals in mammals is an important skill, thought to be mediated by a distributed array of neural networks, including those processing olfactory cues. Recent data from our groups have shown that social memory can be supported by olfactory cues alone and that interactions with an individual lead to increased neural representations of that individual in the anterior olfactory nucleus, an olfactory network strongly modulated by the neuropeptide oxytocin. We here show, using a computational model, how enhanced representations in the AON can easily arise during the encoding phase, how they can be modulated by OXT, and how a dynamic memory signature in the form of enhanced oscillations in the beta range arises from the architecture of the neural networks involved. These findings have implications for our understanding how social memories are formed and retrieved and generate further hypotheses that can be tested experimentally.

Indexed as

MemoryOdorantsOlfactory PathwaysOlfactory PerceptionRecognition, PsychologyReinforcement, PsychologySmellAnimalsComputer SimulationModels, NeurologicalOxytocinOxytocincomputationconspecificlearningmemoryolfactoryoxytocin

Identifiers

PMID40664512
PMCPMC12303586

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.