Evidence map›Paper›PMID 40664501›Full record

ArticleSexually transmitted infections2026

'It does fill me with a bit of unease': a qualitative study of the acceptability, facilitators and barriers to reducing the frequency of screening for asymptomatic sexually transmitted infections among gay, bisexual and other men who have sex with men.

William Berners-Lee, Melissa Cabecinha, James Bell, Dawn Phillips, Tom Witney, Caisey V Pulford, Fabiana Lorencatto, Helen Fifer, Kirsty Foster, Hamish Mohammed and 5 more

Abstract read
In one paragraph

Article in Sexually transmitted infections, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

William Berners-LeeBlood Safety, Hepatitis, Sexually Transmitted Infections (STI) and HIV Division, UK Health Security Agency-Colindale, London, UK bill.berners-lee@ukhsa.gov.uk.ORCID 0009-0004-5519-193X
Melissa CabecinhaResearch Department for Primary Care and Population Health, UCL, London, UK.
James BellBlood Safety, Hepatitis, Sexually Transmitted Infections (STI) and HIV Division, UK Health Security Agency-Colindale, London, UK.ORCID 0000-0002-2265-1205
Dawn PhillipsBlood Safety, Hepatitis, Sexually Transmitted Infections (STI) and HIV Division, UK Health Security Agency-Colindale, London, UK.
Tom WitneyDepartment of Infection and Population Health, UCL, London, UK.ORCID 0000-0003-2695-0605
Caisey V PulfordBlood Safety, Hepatitis, Sexually Transmitted Infections (STI) and HIV Division, UK Health Security Agency-Colindale, London, UK.
Fabiana LorencattoCentre for Behaviour Change, UCL, London, UK.
Helen FiferBlood Safety, Hepatitis, Sexually Transmitted Infections (STI) and HIV Division, UK Health Security Agency-Colindale, London, UK.
Kirsty FosterBlood Safety, Hepatitis, Sexually Transmitted Infections (STI) and HIV Division, UK Health Security Agency-Colindale, London, UK.
Hamish MohammedBlood Safety, Hepatitis, Sexually Transmitted Infections (STI) and HIV Division, UK Health Security Agency-Colindale, London, UK.ORCID 0000-0002-2060-7286
Katy SinkaBlood Safety, Hepatitis, Sexually Transmitted Infections (STI) and HIV Division, UK Health Security Agency-Colindale, London, UK.
Deborah WilliamsonBlood Safety, Hepatitis, Sexually Transmitted Infections (STI) and HIV Division, UK Health Security Agency-Colindale, London, UK.
Greta RaitInstitute of Epidemiology and Health, University College London, London, UK.
Kate FolkardBlood Safety, Hepatitis, Sexually Transmitted Infections (STI) and HIV Division, UK Health Security Agency-Colindale, London, UK.
John SaundersBlood Safety, Hepatitis, Sexually Transmitted Infections (STI) and HIV Division, UK Health Security Agency-Colindale, London, UK.ORCID 0000-0003-3020-9916

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe study aimed to explore the acceptability of reducing the frequency of asymptomatic

methodsThis qualitative study explored stakeholder perspectives on reducing screening frequency and identified potential interventions that could support future guideline changes of this kind. Semistructured interviews were conducted with 22 GBMSM and 8 professional stakeholders. Data were thematically analysed using the Capabilty, Opportunity, Motivation - Behaviour (COM-B) and Theoretical Domains Framework (TDF). TDF domains were mapped to behaviour change techniques to inform intervention development. Candidate interventions were refined based on acceptability, practicability, effectiveness, affordability, side effects, equity.

resultsOverall, GBMSM stakeholder responses to discontinuing asymptomatic Ng and Ct screening tended to be negative, while professional stakeholder opinions were mixed. Reducing the recommended screening frequency to 6 monthly was generally more acceptable to both groups. Barriers and facilitators to guideline changes included issues of knowledge and trust, social influence and identity, context and resources, concerns about consequences and emotional responses and habit. Ten candidate interventions were suggested. These involve providing information, social support, behavioural substitutions and feedback as well as facilitating discussions to resolve concerns.

conclusionAny reduction in the recommended frequency of asymptomatic screening will encounter a range of interrelated barriers, including knowledge gaps, social influences and emotional factors. We identified evidence-based interventions that could improve acceptance and minimise unintended consequences. Future research should incorporate stakeholder workshops to refine these strategies.

Indexed as

Chlamydia InfectionsGonorrheaHomosexuality, MaleMass ScreeningPatient Acceptance of Health CareSexual and Gender MinoritiesSexually Transmitted DiseasesAdultAsymptomatic InfectionsChlamydia trachomatisHumansMaleNeisseria gonorrhoeaeQualitative ResearchYoung AdultChalmydia TrachomatisDiagnostic Screening ProgramsNEISSERIA GONORRHOEAEQUALITATIVE RESEARCHSEXUAL HEALTH

Identifiers

PMID40664501
PMCPMC12911560

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.