ArticleAging2025
Assessment of lipid parameters and its association with risk of stage 1 hypertension: a cohort study in middle-aged and elderly Chinese.
Article in Aging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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18 authors.
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Abstract
backgroundThere is a correlation between dyslipidemia and elevated blood pressure, but the relationship between different lipid parameters and elevated blood pressure is inconsistent. Therefore, understanding the impact of dyslipidemia on blood pressure is significant for the prevention and control of ASCVD. Our study is aimed at assessing longitudinally the correlation between lipid parameters and the incidence of stage 1 hypertension in a large Chinese community population.
methodsThis community-based cohort study conducted from 2011 to 2014-2016 included 2,843 eligible individuals aged 40 years or older. The diagnosis of stage 1 hypertension was systolic blood pressure (SBP) 130~139 mmHg and/or diastolic blood pressure (DBP) 80~89 mmHg. We collect data through standardized questionnaires and clinical and biochemical measurements conducted in unified institutions. The relationship between lipid parameters and risk of stage 1 hypertension were estimated using multiple Cox regression analysis.
resultsDuring the follow-up period, 388 subjects (13.7%) developed stage 1 hypertension. Incidence of stage 1 hypertension gradually increased with the quartiles of triglycerides (TG) and the ratio of TG to high-density lipoprotein cholesterol (TG/HDL-C, all
conclusionsOur study findings suggest that TG/HDL-C is independently associated with the incidence of stage 1 hypertension in the Chinese middle-aged and elderly population.
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