ArticleJournal of speech, language, and hearing research : JSLHR2025
Prelinguistic Communication Complexity of Children With Neurogenetic Syndromes.
Article in Journal of speech, language, and hearing research : JSLHR, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
purposeCommunication complexity and communicative function are important features of prelinguistic communication that are related to later language outcomes. However, little is known about how these early prelinguistic features present in young children with neurogenetic syndromes (NGS). This study aims to characterize prelinguistic complexity and function of children with three NGS: Angelman syndrome (AS), Down syndrome (DS) and fragile X syndrome (FXS).
methodSeventy-two infants aged 5-31 months (16 AS, 24 DS, 13 FXS, 19 low-risk control [LRC] infants) completed a parent-child interaction from which their prelinguistic communication was coded using the Communication Complexity Scale. Communication complexity (degree to which eye gaze, gestures, and vocalizations are integrated) and function (communication for the purposes of joint attention or behavior regulation) were compared among groups.
resultsThe DS group used the most complex communication of the syndrome groups and in many ways demonstrated similar profiles to the LRC group. The AS and FXS groups exhibited the lowest overall communication complexity when covarying age, but their levels of complexity were similar to those of the LRC group when accounting for developmental level. The DS group showed a relative strength in communication for the purposes of behavior regulation. The FXS group demonstrated the lowest likelihood of using communication for the purposes of joint attention, while the AS group exhibited the lowest likelihood of communicating for the purposes of behavior regulation.
conclusionsChildren with NGS exhibit nuanced differences in prelinguistic communication profiles that indicate unique strengths and areas of need. Additional work is needed to disentangle the effects of age and developmental level on prelinguistic communication profiles and to explore how these profiles are related to later language outcomes. Continuing to explore cross-group differences in prelinguistic communication may facilitate more targeted intervention and sensitive phenotyping among children with rare NGS.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.