Evidence map›Paper›PMID 40664229›Full record

Trial reportAmerican journal of respiratory and critical care medicine2025

Endotypes of

Rebecca C Hull, Jamie Stobo, Hani Abo-Leyah, Hollian Richardson, Daniela Alferes de Lima Headley, Merete B Long, Chandani Hennayake, Amy Gilmour, Emma D Johnson, Michael Tunney and 5 more

Abstract readClinical Trial, Phase IIIRandomized Controlled Trial
In one paragraph

Trial report in American journal of respiratory and critical care medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Guideline
  2. Pooled it
  3. Endotypes ofAmerican journal of respiratory and critical care medicine · 2025
    Trial
  4. Article
  5. Article
  6. Review
  7. Factors governing the response ofFrontiers in cellular and infection microbiology · 2026
    Review
  8. Review
  9. Beyond ORBIT: Mapping the Constellation of Pseudomonas Endotypes in Bronchiectasis Clinical Trials.American journal of respiratory and critical care medicine · 2025
    Article
  10. Observational
  11. Microbiome and its role in bronchiectasis.Therapeutic advances in respiratory disease
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors.

Rebecca C HullDivision of Respiratory Medicine and Gastroenterology.ORCID 0009-0004-2014-6354
Jamie StoboDivision of Respiratory Medicine and Gastroenterology.ORCID 0000-0003-4829-7440
Hani Abo-LeyahDivision of Respiratory Medicine and Gastroenterology.ORCID 0000-0001-7572-2153
Hollian RichardsonDivision of Respiratory Medicine and Gastroenterology.
Daniela Alferes de Lima HeadleyDivision of Respiratory Medicine and Gastroenterology.
Merete B LongDivision of Respiratory Medicine and Gastroenterology.
Chandani HennayakeDivision of Respiratory Medicine and Gastroenterology.
Amy GilmourDivision of Respiratory Medicine and Gastroenterology.
Emma D JohnsonDivision of Respiratory Medicine and Gastroenterology.
Michael TunneySchool of Pharmacy, Queen's University Belfast, Belfast, United Kingdom; and.
Alison J DickerDivision of Population Health and Genomics, and.
Eleanor KewinDivision of Population Health and Genomics, and.
Jeffrey T J HuangDivision of Cardiovascular Research, University of Dundee, Ninewells Hospital and Medical School, Dundee, United Kingdom.
Charles S HaworthCambridge Centre for Lung Infection, Royal Papworth Hospital and University of Cambridge, Cambridge, United Kingdom.
James D ChalmersDivision of Respiratory Medicine and Gastroenterology.ORCID 0000-0001-5514-7868

Funding

European Respiratory SocietyHorizon 2020 Framework ProgramInhaled Antibiotic for Bronchiectasis and Cystic Fibrosis 115721
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Anti-Bacterial AgentsBronchiectasisCiprofloxacinPseudomonas aeruginosaPseudomonas InfectionsAdministration, InhalationAgedDouble-Blind MethodFemaleHumansMaleMicrobiotaMiddle AgedSputumTreatment OutcomeAnti-Bacterial AgentsCiprofloxacinbronchiectasisciprofloxacininflammationmicrobiotaPseudomonas aeruginosa

Identifiers

PMID40664229
PMCPMC12369955

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.