Evidence map›Paper›PMID 40663791›Full record

ArticleJMIR dermatology2025

Exploring Attention-Deficit/Hyperactivity Disorder Symptoms in Patients With Atopic Dermatitis by Disease Severity: Cross-Sectional Analysis.

Amr Molla, Raed Jannadi, Dareen Hafez, Lujain Alrohaily, Ebtesam Abdullah, Duha Azouni, Muayad Albadrani

Abstract readMulticenter Study
In one paragraph

Article in JMIR dermatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Amr MollaDepartment of Medicine, College of Medicine, Taibah University, P.O.Box 344, Unit 99, Madinah, 42319, Saudi Arabia, 996 0504342992.ORCID 0000-0002-4743-5365
Raed JannadiDepartment of Family and Community Medicine and Medical Education, College of Medicine, Taibah University, Madinah, Saudi Arabia.ORCID 0009-0002-8256-1508
Dareen HafezDepartment of Child & Adolescent Psychiatry, King Salman Medical City, Madinah, Saudi Arabia.ORCID 0009-0005-5132-6136
Lujain AlrohailyDepartment of Pediatric, King Salman Medical City, Madinah, Saudi Arabia.ORCID 0009-0009-8585-3814
Ebtesam AbdullahDepartment of Medicine, King Fahad Hospital, Madinah, Saudi Arabia.ORCID 0009-0006-2309-2683
Duha AzouniDepartment of Medicine, King Fahad Hospital, Madinah, Saudi Arabia.ORCID 0009-0000-3324-0092
Muayad AlbadraniDepartment of Family and Community Medicine and Medical Education, College of Medicine, Taibah University, Madinah, Saudi Arabia.ORCID 0000-0002-7486-1677

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Atopic dermatitis (AD) is a chronic inflammatory skin condition affecting a significant percentage of the global population. Emerging research suggests a potential link between AD and neurodevelopmental disorders like attention-deficit/hyperactivity disorder (ADHD). However, there is a lack of comprehensive studies within the Saudi Arabian population examining this association. Objective: This study aims to determine the prevalence of ADHD among patients with AD in Saudi Arabia and to explore potential associations with demographic and clinical factors. Methods: In this cross-sectional, multicenter study conducted between May and November 2024, 419 patients with AD were recruited from various hospitals in Saudi Arabia. Children were screened for ADHD symptoms using the ADHD Rating Scale-5, while adults were assessed with the Adult Self-Report Scale. Logistic regression was used to evaluate the influence of AD severity, age, gender, nationality, and BMI on the likelihood of ADHD symptoms. Results: A total of 419 patients with AD were included, of whom 234 (55.8%) were children and 185 (44.2%) were adults; 239 (57%) were female and 360 (85.9%) were Saudi nationals. ADHD symptoms were identified in 84 (20%) patients, with a slightly higher prevalence among children (49/234, 20.9%) compared to adults (35/185, 18.9%; P=.61). No significant associations were found between ADHD symptoms and gender, nationality, BMI, or AD severity in either age group. Moderate to severe AD was more common among adults (48/185, 25.9%) than children (42/234, 17.9%; P=.048). Conclusions: This study found that 20% of patients with AD screened positive for ADHD symptoms, with slightly higher rates in children than adults. No significant associations were observed between ADHD symptoms and gender, nationality, BMI, or AD severity. Although no significant clinical predictors were identified, the findings emphasize the need for ADHD screening in patients with AD, particularly in regions with high AD prevalence. Future longitudinal studies should explore underlying mechanisms and assess how managing one condition may influence the other.

Indexed as

Attention Deficit Disorder with HyperactivityDermatitis, AtopicAdolescentAdultChildChild, PreschoolCross-Sectional StudiesFemaleHumansMaleMiddle AgedPrevalenceSaudi ArabiaSeverity of Illness IndexYoung AdultADHDatopic dermatitisattention-deficit/hyperactivity disordercross-sectional studyneurodevelopmental disorders

Identifiers

PMID40663791
PMCPMC12283059

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.