Evidence map›Paper›PMID 40663610›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2025

A genetically defined pontine nucleus essential for ingestion in mice.

Selvee Sungeelee, Caroline Mailhes-Hamon, Zoubida Chettouh, Phillip Bokiniec, Annaliese Eymael, Simon McMullan, Clément Léna, Bowen Dempsey, Jean-François Brunet

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Into the belly of the brainstem: The neurons of the "extended" enteric nervous system.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Selvee SungeeleeInstitut de Biologie de l'ENS, Inserm, Centre national de la recherche scientifique, École normale supérieure, Paris Sciences & Lettres Research University, Paris 75005, France.ORCID 0000-0001-8449-8798
Caroline Mailhes-HamonInstitut de Biologie de l'ENS, Inserm, Centre national de la recherche scientifique, École normale supérieure, Paris Sciences & Lettres Research University, Paris 75005, France.
Zoubida ChettouhInstitut de Biologie de l'ENS, Inserm, Centre national de la recherche scientifique, École normale supérieure, Paris Sciences & Lettres Research University, Paris 75005, France.
Phillip BokiniecQueensland Brain Institute, University of Queensland, Brisbane, QLD 4072, Australia.
Annaliese EymaelFaculty of Medicine, Health and Human Sciences, School of medicine, Macquarie University, Macquarie Park, NSW 2109, Australia.
Simon McMullanFaculty of Medicine, Health and Human Sciences, School of medicine, Macquarie University, Macquarie Park, NSW 2109, Australia.ORCID 0000-0002-9854-1029
Clément LénaInstitut de Biologie de l'ENS, Inserm, Centre national de la recherche scientifique, École normale supérieure, Paris Sciences & Lettres Research University, Paris 75005, France.ORCID 0000-0002-1431-7717
Bowen Dempsey *Faculty of Medicine, Health and Human Sciences, School of medicine, Macquarie University, Macquarie Park, NSW 2109, Australia.
Jean-François Brunet *Institut de Biologie de l'ENS, Inserm, Centre national de la recherche scientifique, École normale supérieure, Paris Sciences & Lettres Research University, Paris 75005, France.ORCID 0000-0002-1985-6103

Funding

Agence Nationale de la Recherche (ANR) ANR-17-CE16-0006-01Agence Nationale de la Recherche (ANR) ANR-19-CE16-0029-177 01Fondation pour la Recherche Médicale (FRM) FRM EQU202003010297National Health & Medical Research Council of Australia APP2001128
6 · The paper itself

Abstract

The first phase of feeding consists in the procurement of solid foods from the environment by biting, and their preparation for swallowing by chewing. These actions require the precise coordination of tens of orofacial muscles for the jaw and tongue. The seat for this motor patterning is known to reside in the reticular formation, a complex and poorly mapped region of the hindbrain, but the neuron groups involved are still elusive. Here, we characterize a group of excitatory reticular interneurons located in the supratrigeminal area that express the homeodomain transcription factor

Indexed as

DeglutitionEatingHomeodomain ProteinsPonsAnimalsInterneuronsMaleMasticationMiceMice, TransgenicMotor NeuronsOptogeneticsTranscription FactorsHomeodomain ProteinsPhox2b protein, mouseTranscription Factorsbrainstemfeedingmotor systemsorofacial movementssystems neuroscience

Identifiers

PMID40663610
PMCPMC12305073

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.