Evidence map›Paper›PMID 40663501›Full record

ArticleJournal of natural products2025

Bletistrosides M-X, Anti-Alzheimer's Disease Compounds from the Tubers of

Zhiwei Bian, Xiaoying Liu, Jiaxuan Li, Shian Hu, Yeun-Mun Choo, Zeyu Zhao, Jinfeng Hu, Kangrui Ji, Mark T Hamann, Xin Wang and 1 more

Abstract read
In one paragraph

Article in Journal of natural products, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Zhiwei BianSchool of Pharmacy, Lanzhou University, Lanzhou, Gansu 730000, P. R. China.
Xiaoying LiuSchool of Pharmacy, Lanzhou University, Lanzhou, Gansu 730000, P. R. China.
Jiaxuan LiSchool of Pharmacy, Lanzhou University, Lanzhou, Gansu 730000, P. R. China.
Shian HuSchool of Pharmacy, Lanzhou University, Lanzhou, Gansu 730000, P. R. China.
Yeun-Mun ChooChemistry Department, Faculty of Science, University of Malaya, 50603 Kuala Lumpur, Malaysia.ORCID 0000-0001-9891-5898
Zeyu ZhaoInstitute of Natural Medicine and Health Products, School of Pharmaceutical Sciences, Zhejiang Provincial Key Laboratory of Plant Evolutionary Ecology and Conservation, Taizhou University, Taizhou Zhejiang 318000, PR China.
Jinfeng HuInstitute of Natural Medicine and Health Products, School of Pharmaceutical Sciences, Zhejiang Provincial Key Laboratory of Plant Evolutionary Ecology and Conservation, Taizhou University, Taizhou Zhejiang 318000, PR China.
Kangrui JiGlasgow International College, University of Glasgow, Glasgow, G11 6NU, Scotland United Kingdom.
Mark T HamannDrug Discovery, Biomedical Sciences and Public Health, Medical University of South Carolina, Charleston, South Carolina 29425, United States.ORCID 0000-0002-3798-4002
Xin WangSchool of Pharmacy, Lanzhou University, Lanzhou, Gansu 730000, P. R. China.
Xiaojuan WangSchool of Pharmacy, Lanzhou University, Lanzhou, Gansu 730000, P. R. China.ORCID 0000-0001-5559-6997

Funding

Synthesis and Optimization of the Aleutianamine Class of AlkaloidsR01GM145845 · NIGMS · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI HAMANN, MARK T, TIUS, MARCUS ANTONIUS · 2022 to 2025
$2.4M
Natural Product HCV Drugs from Rare Plant-Microbe InteractionsR01AT007318 · NCCIH · UNIVERSITY OF MISSISSIPPI · PI HAMANN, MARK T · 2012 to 2016
$1.6M
NCCIH NIH HHS R01 AT007318NIGMS NIH HHS R01 GM145845
6 · The paper itself

Abstract

Twelve new compounds, bletistrosides M-X (

Indexed as

Alzheimer DiseaseOrchidaceaePlant TubersAmyloid beta-PeptidesAnimalsGlycosidesHumansMolecular StructureAmyloid beta-PeptidesGlycosides

Identifiers

PMID40663501
PMCPMC12624762

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.