Evidence map›Paper›PMID 40663383›Full record

ArticleVirulence2025

Mechanistic study of the immune defense function of the CRISPR1-Cas system in

Shuan Tao, Yewei Fang, Lin Zheng, He Zhang, Yao Xu, Wei Liang

Abstract read
In one paragraph

Article in Virulence, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Shuan TaoDepartment of Clinical Laboratory, The First Affiliated Hospital of Ningbo University, Ningbo, China.ORCID 0000-0001-9813-8814
Yewei FangDepartment of Clinical Laboratory, The First Affiliated Hospital of Ningbo University, Ningbo, China.
Lin ZhengDepartment of Clinical Laboratory, The First Affiliated Hospital of Ningbo University, Ningbo, China.
He ZhangDepartment of Medical Laboratory, Bengbu Medical College, Bengbu, China.
Yao XuSchool of Medicine, Ningbo University, Ningbo, China.
Wei LiangDepartment of Clinical Laboratory, The First Affiliated Hospital of Ningbo University, Ningbo, China.ORCID 0000-0002-1610-0554

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Enterococci are Gram-positive cocci that are considered to be one of the causative agents of hospital-acquired infections. CRISPR-Cas is an adaptive immune system with targeted defense functions against foreign invading nucleic acids and plays an important role in antibiotic resistance. In this study, we aimed to investigate II-A CRISPR-Cas-mediated immunity and the molecular mechanism underlying the horizontal transfer of drug resistance genes in

Indexed as

CRISPR-Cas SystemsEnterococcus faecalisDrug Resistance, BacterialGene Transfer, HorizontalMutationPlasmidsTransformation, Bacterialantibiotic resistanceCRISPR-CasEnterococcus faecalisimmune defense mechanism

Identifiers

PMID40663383
PMCPMC12269653

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.