Evidence map›Paper›PMID 40663344›Full record

ArticleJournal of the American Chemical Society2025

NMR-Guided Studies to Establish the Binding Interaction between a Peptoid and Protein.

Christine S Muli, Dan Xie, Carol Beth Post, Darci J Trader

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the American Chemical Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Christine S MuliBorch Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, 575 West Stadium Avenue, West Lafayette, Indiana 47907, United States.
Dan XieBorch Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, 575 West Stadium Avenue, West Lafayette, Indiana 47907, United States.
Carol Beth PostBorch Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, 575 West Stadium Avenue, West Lafayette, Indiana 47907, United States.ORCID 0000-0002-5233-899X
Darci J TraderBorch Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, 575 West Stadium Avenue, West Lafayette, Indiana 47907, United States.ORCID 0000-0002-0607-1243

Funding

Transgenic Mouse Core Facility Shared Resource (TMCF-SR)P30CA023168 · NCI · PURDUE UNIVERSITY WEST LAFAYETTE · PI ANDREW D MESECAR · 1985 to 2026
$43.4M
NMR Structure of Peptide and Protein Complexes SupplementR01GM039478 · NIGMS · PURDUE UNIVERSITY WEST LAFAYETTE · PI POST, CAROL B. · 1997 to 2024
$6.5M
Investigating the Interaction of a Selective Peptoid Probe and Rpn-13, A Non-Essential Ubiquitin Receptor of the ProteasomeF31CA247327 · NCI · PURDUE UNIVERSITY · PI MULI, CHRISTINE S · 2020 to 2022
$124k
NCI NIH HHS F31 CA247327NCI NIH HHS P30 CA023168NIGMS NIH HHS R01 GM039478
6 · The paper itself

Abstract

Ligand discovery of nonenzymatic proteins can be accomplished through screening methods utilizing libraries comprising small molecules, peptides, and peptidomimetics. Incorporating peptoids, which are oligomers of

Indexed as

PeptoidsBinding SitesMolecular Dynamics SimulationNuclear Magnetic Resonance, BiomolecularProtein BindingPeptoids

Identifiers

PMID40663344
PMCPMC12310119

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.