Evidence map›Paper›PMID 40663330›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2025

Parallel Synthesis of Glycopeptide Libraries Using Glyco-SPOT Synthesis.

Akul Y Mehta, Jamie Heimburg-Molinaro, Richard D Cummings

Abstract read
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In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Akul Y MehtaDepartment of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA. aymehta@bidmc.harvard.edu.
Jamie Heimburg-MolinaroDepartment of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
Richard D CummingsDepartment of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Synthesis of glycopeptide libraries is often limited by the cost and availability of the glycoamino acids. To circumvent this, we have devised a method of using SPOT synthesis for production of such libraries using cellulose filter paper as the solid support. We termed this method Glyco-SPOT synthesis, and it can be used to produce libraries of glycopeptides in microgram quantities in a parallel manner using microgram amounts of glycoamino acids. This chapter provides details on the method to perform this synthesis process.

Indexed as

GlycopeptidesPeptide LibrarySolid-Phase Synthesis TechniquesGlycopeptidesPeptide LibraryGlycansGlycopeptidesGlycosulfopeptidesSpot synthesis

Identifiers

PMID40663330

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.