Evidence map›Paper›PMID 40663245›Full record

ReviewDiscover oncology2025

The role of long noncoding RNA SNHG29 in malignant tumors.

Tingcheng Bu, Wendong Gu, Yingjie Shao

Abstract readReview
In one paragraph

Review in Discover oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Tingcheng BuDepartment of Radiation Oncology, The Third Affiliated Hospital of Soochow University, 185 Juqian Street, Changzhou, 213003, China.
Wendong GuDepartment of Radiation Oncology, The Third Affiliated Hospital of Soochow University, 185 Juqian Street, Changzhou, 213003, China. guwendong1415@czfph.com.
Yingjie ShaoDepartment of Radiation Oncology, The Third Affiliated Hospital of Soochow University, 185 Juqian Street, Changzhou, 213003, China. shaoyingjie@suda.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Long noncoding RNAs (lncRNAs), defined as noncoding transcripts exceeding 200 nucleotides without protein-coding potential, have been increasingly recognized for encoding polipeptides or proteinsimplicated in the regulation of malignant tumor initiation, progression, and prognosis. Among them, small nucleolar RNA host gene 29 (SNHG29) has attracted increasing attention because of its aberrant expression across diverse malignancies. This report reviews the latest research regarding its expression patterns, regulatory functions, and involved signaling pathways. This review synthesizes current insights into the contributions of SNHG29 to oncogenic processes, including cell proliferation, migration, epithelial‒mesenchymal transition, chemoresistance, and immunosuppression. Furthermore, evidence indicates that SNHG29 functions as a competing endogenous RNA (ceRNA), modulating tumor progression via the miRNA‒mRNA axis and signaling pathways such as the ATR‒Chk1, PI3K‒AKT, and Wnt‒β-catenin pathways. Cumulative data position SNHG29 as a promising diagnostic and prognostic biomarker, as well as a potential molecular target for therapeutic intervention in various malignancies.

Indexed as

BiomarkerHuman cancerLong noncoding RNAPrognosisSNHG29

Identifiers

PMID40663245
PMCPMC12263534

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.