Evidence map›Paper›PMID 40663172›Full record

SynthesisJournal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie2026

Effectiveness of piezoelectric-assisted orthodontic treatment : Systematic review and meta-analysis of randomized controlled trials.

Christopher Liang-Cheng Chen, Shao-Yu Wang, Min-Jia Tsai, Tsai-Wei Huang

Abstract readSystematic ReviewMeta-Analysis
PubMed Publisher
In one paragraph

Synthesis in Journal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Christopher Liang-Cheng ChenDivision of Oral and Maxillofacial Surgery, Dental Department, Changhua Christian Hospital, Changhua, Taiwan.
Shao-Yu WangDental Department, Changhua Christian Hospital, Changhua, Taiwan.
Min-Jia TsaiDepartment of Dentistry, China Medical University Hospital, Taichung, Taiwan.
Tsai-Wei HuangSchool of Nursing, College of Nursing, Taipei Medical University, 250, Wuxing Street, 11031, Taipei, Taiwan. tsaiwei@tmu.edu.tw.ORCID https://orcid.org/0000-0002-6722-1153

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOrthodontic treatment offers numerous benefits, but prolonged treatment times can lead to increased costs and sequelae. Piezoelectric-assisted procedures like piezocision show promise in accelerating treatment, though their efficacy is not yet fully confirmed, nor are they widely adopted. This study aimed to evaluate the effectiveness of piezocision for orthodontic patients.

methodsA meta-analysis of 16 randomized controlled trials (RCTs) involving 371 patients was conducted to compare piezocision with conventional orthodontic treatment. Systematic searches were performed in PubMed, EMBASE, and Cochrane Library databases. Statistical analyses included mean difference (MD) with 95% confidence intervals (CI) using a random-effects model. The study protocol was registered in PROSPERO (CRD42022335350).

resultsPiezocision significantly reduced treatment duration compared to conventional methods (MD = -39.60, 95% CI -59.67 to -19.52), though total treatment time was investigated by only one research group. Posttreatment pain was significantly higher in the piezocision group on day 1 (MD = 17.83, 95% CI 5.75-29.92) but showed no significant differences on day 7 (MD = 4.86, 95% CI -0.74 to 10.47). Despite similar pain levels by day 7, patients expressed preferences for conventional orthodontic treatment. The reduction rate of Little's irregularity index was more efficient in the piezocision group during the first month (MD = 1.58, 95% CI -0.13 to 3.29), with no significant differences at the end of alignment (MD = 1.04, 95% CI -0.06 to 2.15).

conclusionPiezocision resulted in reduced orthodontic treatment duration compared to conventional methods. However, considering the study limitations and patient preferences, future research with larger sample sizes and more RCTs is needed to validate these findings and assess the long-term clinical implications before widespread adoption.

Indexed as

MalocclusionOrthodontics, CorrectivePiezosurgeryPostoperative PainAdolescentChildFemaleHumansMalePrevalenceRandomized Controlled Trials as TopicRisk FactorsTreatment OutcomeAcceleratory proceduresCorticotomyPiezocisionPosttreatment painRandomized controlled trials

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.