Evidence map›Paper›PMID 40663148›Full record

ArticleAnalytical and bioanalytical chemistry2025

Sensitive electrochemical sensor based on hybrid material F-doped carbon quantum dots (Cdots) and NiO nanoparticles: detection of ketoconazole in pharmaceutical formulations and tap water samples.

Carolina Meneses Dos Santos, Francisco Walison Lima Silva, Octávio P L de Souza, Thiago C Canevari, Ricardo Erthal Santelli, Vivian M Saez, Fernando Henrique Cincotto

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Article in Analytical and bioanalytical chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Carolina Meneses Dos SantosDepartment of Analytical Chemistry, Chemical Institute, Universidade Federal Do Rio de Janeiro, Rio de Janeiro, RJ, 21941-909, Brazil.
Francisco Walison Lima SilvaDepartment of Analytical Chemistry, Chemical Institute, Universidade Federal Do Rio de Janeiro, Rio de Janeiro, RJ, 21941-909, Brazil.
Octávio P L de SouzaLabNaHm: Multifunctional Hybrid Nanomaterials Laboratory, Engineering School, Mackenzie Presbyterian University, São Paulo, SP, 01302-907, Brazil.
Thiago C CanevariLabNaHm: Multifunctional Hybrid Nanomaterials Laboratory, Engineering School, Mackenzie Presbyterian University, São Paulo, SP, 01302-907, Brazil.
Ricardo Erthal SantelliDepartment of Analytical Chemistry, Chemical Institute, Universidade Federal Do Rio de Janeiro, Rio de Janeiro, RJ, 21941-909, Brazil.
Vivian M SaezDepartment of Analytical Chemistry, Chemical Institute, Universidade Federal Do Rio de Janeiro, Rio de Janeiro, RJ, 21941-909, Brazil.
Fernando Henrique CincottoDepartment of Analytical Chemistry, Chemical Institute, Universidade Federal Do Rio de Janeiro, Rio de Janeiro, RJ, 21941-909, Brazil. fernandocincotto@iq.ufrj.br.

Funding

Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro E-26/204.444/2024Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro E-26/210.304/2022
6 · The paper itself

Abstract

This study presents a novel electrochemical sensor for ketoconazole determination, developed using an advanced hybrid material composed of fluorine-doped carbon quantum dots (F-Cdots) and nickel oxide nanoparticles (NiONPs) to modify a glassy carbon electrode (GCE). The redox behavior of the modified electrode was evaluated using cyclic voltammetry, revealing an irreversible oxidation peak at 0.59 V, associated with the transfer of a single electron. The modified sensor exhibited a performance approximately 50% higher than that of the unmodified GCE. Square wave voltammetry was optimized for quantification, with the best results obtained in 0.1 M phosphate buffer solution (PBS) at pH 9. The sensor exhibited a low detection limit of 7.12 nmol L⁻

Indexed as

CarbonDrinking WaterElectrochemical TechniquesKetoconazoleMetal NanoparticlesNanoparticlesNickelQuantum DotsWater Pollutants, ChemicalElectrodesLimit of DetectionPharmaceutical PreparationsCarbonDrinking WaterKetoconazoleNickelnickel monoxidePharmaceutical PreparationsWater Pollutants, ChemicalCarbon quantum dotsElectrochemical sensorKetoconazoleSquare wave voltammetry

Identifiers

PMID40663148

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.