Evidence map›Paper›PMID 40663004›Full record

ArticleMedicine2025

Clear cell meningioma of the lower lumbar spine without dural attachment: A case report.

Sakura Shiraishi, Kazuya Yokota, Takumi Tomonaga, Taro Mori, Kenichi Kawaguchi, Hirokazu Saiwai, Kazu Kobayakawa, Kiyoshi Tarukado, Makoto Endo, Yoshinao Oda and 1 more

Abstract readCase Reports
In one paragraph

Article in Medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Sakura ShiraishiDepartment of Orthopaedic Surgery, Graduate School of Medical Sciences, Kyushu University, Higashiku, Fukuoka, Japan.
Kazuya YokotaDepartment of Orthopaedic Surgery, Graduate School of Medical Sciences, Kyushu University, Higashiku, Fukuoka, Japan.ORCID 0000-0002-5930-6499
Takumi TomonagaDepartment of Anatomic Pathology, Pathological Sciences, Graduate School of Medical Sciences, Kyushu University, Higashiku, Fukuoka, Japan.
Taro MoriDepartment of Anatomic Pathology, Pathological Sciences, Graduate School of Medical Sciences, Kyushu University, Higashiku, Fukuoka, Japan.
Kenichi KawaguchiDepartment of Orthopaedic Surgery, Graduate School of Medical Sciences, Kyushu University, Higashiku, Fukuoka, Japan.
Hirokazu SaiwaiDepartment of Orthopaedic Surgery, Graduate School of Medical Sciences, Kyushu University, Higashiku, Fukuoka, Japan.
Kazu KobayakawaDepartment of Orthopaedic Surgery, Graduate School of Medical Sciences, Kyushu University, Higashiku, Fukuoka, Japan.
Kiyoshi TarukadoDepartment of Orthopaedic Surgery, Graduate School of Medical Sciences, Kyushu University, Higashiku, Fukuoka, Japan.
Makoto EndoDepartment of Orthopaedic Surgery, Graduate School of Medical Sciences, Kyushu University, Higashiku, Fukuoka, Japan.
Yoshinao OdaDepartment of Anatomic Pathology, Pathological Sciences, Graduate School of Medical Sciences, Kyushu University, Higashiku, Fukuoka, Japan.
Yasuharu NakashimaDepartment of Orthopaedic Surgery, Graduate School of Medical Sciences, Kyushu University, Higashiku, Fukuoka, Japan.

Funding

ZENKYOREN, Ogata Memorial Foundation JP21K16671
6 · The paper itself

Abstract

rationaleClear cell meningioma (CCM) is a rare and aggressive subtype of meningioma, classified as Grade II by the World Health Organization due to its higher recurrence risk. While CCMs predominantly arise in the cerebellopontine angle, intraspinal cases, particularly those without dural attachment, are exceedingly rare and present diagnostic and surgical challenges. PATIENT CONCERNS AND DIAGNOSIS: We report a case of a 66-year-old woman who presented with a one-year history of pain and numbness radiating from the right buttock to the posterior thigh, along with intermittent claudication. Physical examination showed no motor deficits or significant neurological abnormalities. Magnetic resonance imaging revealed a 32 × 16 mm intradural mass at the L5 level with iso-intensity on both T1- and T2-weighted images and uniform contrast enhancement. The lesion was diagnosed as CCM based on pathological examination following tumor resection. INTERVENTIONS AND OUTCOMES: The patient underwent lumbar laminectomy and complete tumor resection. Intraoperatively, the tumor was observed to compress the cauda equina nerve but was nonadherent to the dura mater. A nerve fiber connected the tumor to surrounding neural structures, requiring partial nerve root resection for complete tumor removal. Postoperatively, the patient reported complete resolution of pain, numbness, and gait disturbance. The visual analogue scale scores for leg pain and numbness improved from 7.4 and 7.3 to 0, respectively. The Japanese Orthopaedic Association score improved from 22 to 28 (out of 29). Follow-up magnetic resonance imaging at 1 year showed no evidence of recurrence. LESSONS: CCM without dural attachment is a rare variant of meningioma that presents challenges in diagnosis and surgical management. Complete resection during the first surgery led to favorable outcomes in this case. Although the recurrence rate for this subtype is lower, long-term follow-up with regular imaging is recommended.

Indexed as

Lumbar VertebraeMeningeal NeoplasmsMeningiomaAgedDura MaterFemaleHumansLaminectomyMagnetic Resonance Imagingcase reportclear cell meningiomaimmunohistochemistryMRIspinal tumor

Identifiers

PMID40663004
PMCPMC12262992

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