Evidence map›Paper›PMID 40662654›Full record

ArticleJournal of Korean medical science2025

Effect of

Seung Yeon Ha, Hyo Sook Song, Jin-Young Kim, Youn-Hee Choi, Ji Ha Choi

Abstract read
In one paragraph

Article in Journal of Korean medical science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Seung Yeon HaDepartment of Pharmacology, College of Medicine, Ewha Womans University, Seoul, Korea.ORCID https://orcid.org/0000-0002-8248-7275
Hyo Sook SongDepartment of Pharmacology, College of Medicine, Ewha Womans University, Seoul, Korea.ORCID https://orcid.org/0000-0002-7082-5206
Jin-Young KimDepartment of Pharmacology, College of Medicine, Ewha Womans University, Seoul, Korea.ORCID https://orcid.org/0000-0003-1214-0273
Youn-Hee ChoiInflammation-Cancer Microenvironment Research Center, College of Medicine, Ewha Womans University, Seoul, Korea.ORCID https://orcid.org/0000-0002-7971-9493
Ji Ha ChoiDepartment of Pharmacology, College of Medicine, Ewha Womans University, Seoul, Korea.ORCID https://orcid.org/0000-0003-3678-1032

Funding

National Research Foundation of Korea 2020R1A5A2019210National Research Foundation of Korea NRF-2019R1F1A1054449
6 · The paper itself

Abstract

backgroundSolute carrier family-5 member-8 (SLC5A8) serves as a plasma membrane transporter for monocarboxylates, such as lactate, butyrate, pyruvate, acetate, propionate, nicotinate, and β-hydroxybutyrate. SLC5A8 can suppress colorectal cancer (CRC), and its tumor-suppressive function is mainly associated with butyrate, propionate, and pyruvate, which inhibit histone deacetylase. Although SLC5A8 is an important tumor suppressor, the impact of

methodsCommon

resultsWe identified two common missense single-nucleotide polymorphisms of

conclusionDecreased SLC5A8 expression caused by missense

Indexed as

Mutation, MissenseCell Line, TumorCell MovementCell ProliferationColorectal NeoplasmsHCT116 CellsHumansMonocarboxylic Acid TransportersPolymorphism, Single NucleotideMonocarboxylic Acid TransportersSLC5A8 protein, humanColorectal CancerMissense VariantSLC5A8Tumor-Suppression

Identifiers

PMID40662654
PMCPMC12260602

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.