Evidence map›Paper›PMID 40662639›Full record

ReviewSleep2025

Diagnosis, treatment, and associated outcomes of later-life insomnia: a narrative review.

Christopher N Kaufmann, Soomi Lee, Amy S Berkley, Emerson M Wickwire, David N Neubauer, Junxin Li, Adam P Spira

Abstract readReview
In one paragraph

Review in Sleep, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Christopher N KaufmannDepartment of Health Outcomes and Biomedical Informatics, University of Florida College of Medicine, 1889 Museum Road, Suite 7000, Gainesville, FL, 32611, USA.
Soomi LeeDepartment of Human Development and Family Studies, Center for Healthy Aging, The Pennsylvania State University, University Park, PA, USA.ORCID 0000-0002-7623-3770
Amy S BerkleyUniversity of Kansas School of Nursing, Kansas City, KS, USA.
Emerson M WickwireDepartment of Psychiatry, University of Maryland School of Medicine, Baltimore, MD, USA.
David N NeubauerDepartment of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Junxin LiJohns Hopkins School of Nursing, Baltimore, MD, USA.ORCID 0000-0001-9798-5456
Adam P SpiraDepartment of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA.ORCID 0000-0003-1507-0995

Funding

University of Florida Older Americans Independence Center (OAIC)P30AG028740 · NIA · UNIVERSITY OF FLORIDA · PI Peihua Qiu · 2007 to 2026
$22.8M
Sleep apnea treatment and risk for cognitive decline and Alzheimers diseaseR01AG079391 · NIA · UNIVERSITY OF FLORIDA · PI Christopher Norfleet Kaufmann · 2022 to 2026
$3.1M
mHealth-Facilitated Physical Activity Toward Health (mPATH) for Cognitive Function and Sleep in Low-Income Older AdultsR01AG080613 · NIA · JOHNS HOPKINS UNIVERSITY · PI Junxin Li · 2023 to 2026
$2.4M
Sleep, Pain, Active Social Life, and Inflammation (SPAI)R01HL163226 · NHLBI · UNIVERSITY OF SOUTH FLORIDA · PI LYNN M. MARTIRE · 2023 to 2026
$2.1M
Sedative-Hypnotic Use Patterns and Risk for Cognitive Decline and Alzheimer's DiseaseK01AG061239 · NIA · UNIVERSITY OF FLORIDA · PI KAUFMANN, CHRISTOPHER NORFLEET · 2019 to 2023
$656k
The power of 40 Hz sound/music for older adults with mild cognitive impairmentR21AG078917 · NIA · JOHNS HOPKINS UNIVERSITY · PI LI, JUNXIN · 2022 to 2023
$450k
Sleep Health Profiles in Middle-aged Workers in Relation to Cardiovascular and Cognitive HealthR56AG065251 · NIA · UNIVERSITY OF SOUTH FLORIDA · PI LEE, SOOMI · 2020 to 2020
$412k
National Institute of Health R21AG078917NHLBI NIH HHS R01 HL163226NHLBI NIH HHS R01HL163226NIA NIH HHS K01 AG061239NIA NIH HHS K01AG061239NIA NIH HHS P30 AG028740NIA NIH HHS P30AG028740NIA NIH HHS R01 AG079391NIA NIH HHS R01AG079391NIA NIH HHS R01 AG080613NIA NIH HHS R01AG080613NIA NIH HHS R21 AG078917NIA NIH HHS R56 AG065251NIA NIH HHS R56AG065251
6 · The paper itself

Abstract

Insomnia is highly prevalent in older adults and is associated with a range of health outcomes. Over the past 10 years, there have been several reviews of the literature concerning insomnia and its outcomes among older individuals; however, there is a need for an updated review examining the emerging themes of research in this space to guide clinical practice and research. Accordingly, in this narrative review, we highlight recent research on insomnia in older adults, documenting the evolution of knowledge regarding insomnia and its consequences as people age. Our review describes trends in the prevalence of insomnia and related symptoms in older adults, as well as potential factors contributing to these trends. We also highlight the growing recognition of insomnia-associated outcomes, specifically focusing on brain and heart health. Given challenges in and barriers to identifying and ultimately treating insomnia, we describe shifts in the ways insomnia is treated with applicability to older adults, including through digital therapeutic modalities that have the potential to increase access to evidence-based behavioral therapies. Our review highlights significant advancements in the understanding of insomnia's role in older adults' health and underscores critical priorities for future research. Statement of Significance Insomnia is highly prevalent in older adults and is associated with a growing scope of adverse health outcomes. While barriers exist to its diagnosis and appropriate treatment in older persons, advancements in the field of sleep medicine, such as expanded pharmacological options and digital therapeutics for behavioral sleep treatments, may help address the unmet need for care. Our narrative review seeks to trace these developments in the hopes of spurring future research to address insomnia in the growing population of older adults.

Indexed as

Sleep Initiation and Maintenance DisordersAgedHumansPrevalencediagnosisinsomnianarrative reviewolder adultssleeptreatment

Identifiers

PMID40662639
PMCPMC13396809

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.