Evidence map›Paper›PMID 40662551›Full record

ReviewCurrent pharmaceutical design2026

Unveiling Targeted Approaches to Combat Drug Resistance in Cancer Chemotherapy.

Siddharth, Siddhant, Salahuddin, Avijit Mazumder, Rajnish Kumar, Abhijit Debnath

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current pharmaceutical design, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

SiddharthDepartment of Pharmaceutical Chemistry, Noida Institute of Engineering and Technology (Pharmacy Institute), Plot No-19, Knowledge Park-2, Greater Noida Uttar Pradesh, 201306, India.ORCID 0009-0001-7623-2970
SiddhantDepartment of Pharmaceutical Chemistry, Noida Institute of Engineering and Technology (Pharmacy Institute), Plot No-19, Knowledge Park-2, Greater Noida Uttar Pradesh, 201306, India.ORCID 0009-0005-1131-3031
SalahuddinDepartment of Pharmaceutical Chemistry, Noida Institute of Engineering and Technology (Pharmacy Institute), Plot No-19, Knowledge Park-2, Greater Noida Uttar Pradesh, 201306, India.ORCID 0000-0002-1868-8865
Avijit MazumderDepartment of Pharmaceutical Chemistry, Noida Institute of Engineering and Technology (Pharmacy Institute), Plot No-19, Knowledge Park-2, Greater Noida Uttar Pradesh, 201306, India.
Rajnish KumarDepartment of Pharmaceutical Chemistry, Noida Institute of Engineering and Technology (Pharmacy Institute), Plot No-19, Knowledge Park-2, Greater Noida Uttar Pradesh, 201306, India.
Abhijit DebnathDepartment of Pharmaceutics, Noida Institute of Engineering and Technology (Pharmacy Institute), Plot No-19, Knowledge Park-2, Greater Noida Uttar Pradesh, 201306, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite significant advancements in medical science, cancer continues to be a major cause of morbidity and mortality worldwide. A key factor contributing to this persistent burden is the emergence of resistance to conventional therapeutic modalities, including chemotherapy, radiation therapy, and surgery. This phenomenon of drug resistance significantly hampers the efficacy of these treatments, leading to therapeutic failure and poor clinical outcomes. A detailed understanding of the molecular and cellular mechanisms underlying drug resistance is crucial for devising targeted strategies to overcome these barriers. In this review, we aim to critically assess and highlight various approaches that can effectively reduce chemotherapy resistance, with the goal of improving the therapeutic efficacy of chemotherapy and enhancing overall patient survival.

Indexed as

Antineoplastic AgentsDrug Resistance, NeoplasmMolecular Targeted TherapyNeoplasmsAnimalsHumansAntineoplastic AgentsAnticancerchemotherapycombat drug resistancedrug resistanceradiation therapy.targeted approach

Identifiers

PMID40662551

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.