Evidence map›Paper›PMID 40662510›Full record

ArticlePediatric pulmonology2025

Online Tool for Predicting Severe Cases of Childhood Community-Acquired Pneumonia Based on the PIRO Concept.

Xin Long, Wanling Li, Yuyi Tang, Zhengxiu Luo, Jian Luo, Zhou Fu, Enmei Liu, Ximing Xu, Yu Deng

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pediatric pulmonology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xin LongDepartment of Otolaryngology, Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing, China.
Wanling LiChongqing Key Laboratory of Child Rare Disease in Infection and Immunity, Chongqing, China.
Yuyi TangChongqing Key Laboratory of Child Rare Disease in Infection and Immunity, Chongqing, China.
Zhengxiu LuoChongqing Key Laboratory of Child Rare Disease in Infection and Immunity, Chongqing, China.
Jian LuoChongqing Key Laboratory of Child Rare Disease in Infection and Immunity, Chongqing, China.
Zhou FuDepartment of Respiratory Medicine, Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing, China.
Enmei LiuChongqing Key Laboratory of Child Rare Disease in Infection and Immunity, Chongqing, China.
Ximing XuBig Data Center for Children's Medical Care, Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing, China.
Yu DengChongqing Key Laboratory of Child Rare Disease in Infection and Immunity, Chongqing, China.ORCID https://orcid.org/0000-0002-2864-505X

Funding

All phases of this study were supported by National Key Research and Development Program of China (2022YFC2704900); CQMU Program for Youth Innovation in Future Medicine; 2025 Chongqing Municipality Joint Science and Health Major Medical Research Project (Grant no. 2025DBXM008). The funders of the study had no role in study design, data collection, data analysis, data interpretation, or writing of the report.
6 · The paper itself

Abstract

backgroundPneumonia remains a leading cause of mortality among children under 5 years of age. This study aimed to compare existing prognostic scoring systems and identify the most effective tool for assessing outcomes in children with community-acquired pneumonia (CAP).

methodsThe Predisposition, Insult, Response, and Organ Dysfunction score for CAP (PIRO-CAP) was modified to create the Ch-online PIRO score based on a comprehensive cohort study. This new scoring system was validated in a cohort of 75,965 children under the age of 5 years with CAP, treated at the Children's Hospital of Chongqing Medical University between 2016 and 2021. Effectiveness in predicting severe cases was then compared against the Pediatric Critical Illness Score (PCIS), Pneumonia Etiology Research for Child Health (PERCH) score, and PIRO-CAP score.

resultsThe Ch-online PIRO score retained most of the original PIRO-CAP factors, including age under 6 months, comorbidities, SpO

conclusionThe Ch-online PIRO score shows promise as an effective prognostic tool for assessing the severity of CAP in young children.

Indexed as

Community-Acquired InfectionsPneumoniaSeverity of Illness IndexChild, PreschoolCommunity-Acquired PneumoniaFemaleHumansInfantMalePrognosisRetrospective StudieschildrenCh‐online PIRO scorecommunity‐acquired pneumonia

Identifiers

PMID40662510
PMCPMC12261875

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.