ArticleInternational journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics2026
Oncologic outcome and recurrence patterns of clinical stage IB and IIA cervical cancer: A large retrospective analysis of a tertiary reference center.
Article in International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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4 citing papers in PubMed.
- Prognostic Survival Model Following Primary Radical Surgery for Early-Stage Cervical Cancer.Cancers · 2026Article
- Prognostic factors and outcomes of CT-guided Iodine-125 seed brachytherapy for retroperitoneal lymph node metastases from a previously irradiated field in cervical carcinoma: a multicenter retrospective study.Frontiers in oncology · 2026Article
- Oncologic outcome and recurrence patterns of clinical stage IB and IIA cervical cancer: A large retrospective analysis of a tertiary reference center.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026Article
- Expression levels of serum SCC, HE4, and TSGF in cervical cancer patients and their correlation with recurrence: a retrospective study.Frontiers in medicine · 2026Article
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Abstract
objectiveTo evaluate the outcomes and recurrence patterns and define the parameters that can help to predict high-risk patients among our 20-year clinical early-stage IB-IIA cervical cancer patients treated with traditional (non-nerve sparing) radical surgery.
methodsThis retrospective cohort study included 158 patients who had undergone traditional (non-nerve sparing) radical hysterectomy with pelvic lymph node dissection ± paraaortic lymph node dissection with clinical early-stage IB-IIA cervical cancer between January 2005 and July 2024 in our referral center. Descriptive statistics, survival analyses, and recurrence sites were evaluated. Furthermore, we researched independent risk factors for parametrial involvement and lymph node metastasis in these patients.
resultsThe median follow-up time was 112 (1-288) months. The 5-year disease-free survival and overall survival rates in this study were 84% and 89%, respectively. There were two (1.2%) patients with local recurrence, four (2.4%) with regional, and seven (4.4%) patients with distant recurrence. According to multivariate logistic regression analyses, the only independent risk factor for regional and distant recurrences was lymph node metastasis.
conclusionTraditional (non-nerve sparing) radical surgery appears to be safe and necessary to improve local control and decrease the local recurrence rate in clinical early-stage IB-IIA cervical cancer patients. We observed that lymph node metastasis was the only independent risk factor for regional and distant recurrences. However, there was no independent risk factor for local recurrence in patients with clinical stage IB-IIA cervical cancer.
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