SynthesisActa paediatrica (Oslo, Norway : 1992)2025
Risk Factors for Hearing Loss Are Comparable in Preterm Versus Term Children: A Systematic Review.
Synthesis in Acta paediatrica (Oslo, Norway : 1992), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Outcomes of early-phase ampicillin plus aminoglycosides versus ampicillin plus cefotaxime for preterm infants.Pediatric research · 2026Article
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5 authors.
Funding
Abstract
aimHearing loss occurs more frequently in preterm children. However, the influence of prematurity itself is unclear. We examined whether risk factors for hearing loss differ between preterm and term infants.
methodsWe conducted a systematic search of three databases in March 2023 for studies comparing risk factors for hearing loss in preterm and term children. Studies on postnatal trauma, chemotherapy or infections after the age of 5 years were excluded. Risk of bias was assessed. Data were extracted and analyzed using logistic regression to yield odds ratios (95% confidence interval).
resultsOf 10 300 studies screened, 16 met the inclusion criteria, including 9059 preterm and 10 048 term children. Only one study compared risk factors between preterm and term infants as primary outcomes. It identified an increased risk in the preterm but not term group with mechanical ventilation exceeding 5 days, sepsis, and ototoxic medication. No significant differences were found when both groups shared these risk factors, suggesting that prematurity may not be an independent risk factor. Other studies reported variable results.
conclusionEvidence of different effect sizes of risk factors in preterm and term children remains inconclusive. Preterm children acquire more risk factors in the neonatal period.
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