Evidence map›Paper›PMID 40662188›Full record

ArticleCase reports in oncology

Aggressive Craniospinal Recurrence of a

Abdel Mun'Em S Al Hourani, Peter H Ahn, Yahia M Tagouri, Timothy Deklotz, Jai Singh Rajput, Ankit Madan

Abstract readCase Reports
In one paragraph

Article in Case reports in oncology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Abdel Mun'Em S Al HouraniDepartment of Internal Medicine, MedStar Southern Maryland Hospital Center, Clinton, MD, USA.
Peter H AhnDepartmant of Radiation Medicine, Medstar Georgetown University Hospital, Washington, DC, USA.
Yahia M TagouriDepartment of Pathology, Medstar Georgetown University Hospital, Washington, DC, USA.
Timothy DeklotzDepartment of Otolaryngology, Medstar Georgetown University Hospital, Washington, DC, USA.
Jai Singh RajputDepartment of Family Medicine, Stabler Clinic, Greenville, AL, USA.
Ankit MadanMedStar Georgetown Cancer Institute, Medstar Southern Maryland Hospital Center, Clinton, MD, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Sinonasal teratocarcinosarcoma (SNTCS) is an aggressive and highly recurrent tumor with a predilection for anterior skull base location. It continues to pose a challenge due to difficulty in diagnosis and the lack of large-scale studies on optimal treatment strategies. Case Presentation: We report a case of a 48-year-old female patient who presented with headache, nausea, and vomiting. Initial imaging revealed a 6.4 × 4.5 cm extra-axial mass in the right frontal region, originating from the superior right nasal cavity. She underwent surgical resection of the tumor and was found to have SNTCS. She received concurrent chemoradiotherapy. Next-generation sequencing showed mutations in the Conclusion: SNTCS remains challenging to treat, as despite using surgical resection and concurrent chemoradiotherapy, it continues to have a high recurrence and mortality rate. We further discuss various demographics, chemotherapy regimens, prognosis, and common genetic mutations found in SNTCS.

Indexed as

Craniospinal recurrencePTEN mutationSinonasal teratocarcinosarcomaSMARCA4 mutation

Identifiers

PMID40662188
PMCPMC12258869

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.