Evidence map›Paper›PMID 40662094›Full record

ArticleJournal of skin cancer2025

Epidemiological Trends, Clinical Impact, and Geographical Variations of Nonmelanoma Skin Cancers: A Twelve-Year Study in Messina, Italy.

Gabriele Delia, Fabiana Battaglia, Pasqualina Laganà, Giovanni Genovese, Cristina Genovese, Giuseppe Trimarchi, Roberta Giuffrida, Francesco Stagno d'Alcontres

Abstract read
In one paragraph

Article in Journal of skin cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Gabriele DeliaDepartment of Plastic and Reconstructive Surgery, University Hospital of Messina "AOU Gaetano Martino", Messina, Italy.
Fabiana BattagliaDepartment of Plastic and Reconstructive Surgery, University Hospital of Messina "AOU Gaetano Martino", Messina, Italy.ORCID https://orcid.org/0009-0002-2281-2862
Pasqualina LaganàDepartment of Biomedical, Dental Sciences, and Morphofunctional Imaging, University of Messina, Messina, Italy.
Giovanni GenoveseDepartment of Biomedical, Dental Sciences, and Morphofunctional Imaging, University of Messina, Messina, Italy.
Cristina GenoveseDepartment of Biomedical, Dental Sciences, and Morphofunctional Imaging, University of Messina, Messina, Italy.
Giuseppe TrimarchiSIR, University of Messina, Messina, Italy.
Roberta GiuffridaDepartment of Clinical and Experimental Medicine, Section of Dermatology, University of Messina, Messina 98125, Italy.
Francesco Stagno d'AlcontresDepartment of Plastic and Reconstructive Surgery, University Hospital of Messina "AOU Gaetano Martino", Messina, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The incidence of nonmelanoma skin cancers (NMSCs), including basal cell carcinoma (BCC) and cutaneous squamous cell carcinoma (cSCC), is increasing globally, driven by factors such as chronic UV exposure, climate change, and aging populations. This comprehensive retrospective cohort study examined 1252 patients treated for NMSCs at the Plastic Surgery Unit of the University of Messina, Italy, from 2012 to 2023. The study aimed to assess demographic characteristics, histological types, lesion attributes, recurrence rates, and geographical variations in NMSC incidence. Beyond confirming global epidemiological trends, this study highlights clinically relevant factors influencing tumor presentation, including environmental risk exposure, lesion recurrence, and histological aggressiveness. Data were collected on patient demographics, tumor location, histological subtype, lesion diameter, presence of ulceration, recurrence, and differentiation grade. Statistical analysis was conducted using R software (Version 4.2.0). Findings demonstrated that patients residing in coastal areas had a significantly higher incidence of NMSCs, reinforcing the role of exposure and environmental pollutants in carcinogenesis. These findings align with global trends and highlight the urgent need for early diagnosis, targeted dermatological surveillance, and public health interventions to mitigate the rising burden of NMSCs. The study underscores the necessity of enhanced sun protection awareness, integration of dermatological screenings in primary care settings, and improved treatment protocols to reduce recurrence and morbidity.

Indexed as

clinical managementgeographic variation in cancerhistopathological analysisnonmelanoma skin cancerpublic health interventionskin cancer epidemiology

Identifiers

PMID40662094
PMCPMC12259310

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.