Evidence map›Paper›PMID 40662066›Full record

ArticleFrontiers in medicine2025

Investigating STLV-1 infection in African green monkeys: a model for understanding HTLV-1 pathogenesis.

Víctor  Folgosi, Liliane A Carneiro, Sabri S Sanabani, Felipe B Freitas, Mayara N S da Silva, Amanda L Silva, Gerlane N Noronha, Ariela S Farias, Hebert F Culler, Carlos F Apoliano and 7 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Víctor  FolgosiSchool of Medicine, University of São Paulo, São Paulo, Brazil.
Liliane A CarneiroNational Center for Primate (CENP), Belém, Brazil.
Sabri S SanabaniSchool of Medicine, University of São Paulo, São Paulo, Brazil.
Felipe B FreitasEvandro Chagas Institute, Ananindeua, Brazil.
Mayara N S da SilvaEvandro Chagas Institute, Ananindeua, Brazil.
Amanda L SilvaSchool of Medicine, University of São Paulo, São Paulo, Brazil.
Gerlane N NoronhaNational Center for Primate (CENP), Belém, Brazil.
Ariela S FariasNational Center for Primate (CENP), Belém, Brazil.
Hebert F CullerSchool of Medicine, University of São Paulo, São Paulo, Brazil.
Carlos F ApolianoSchool of Medicine, University of São Paulo, São Paulo, Brazil.
Luciano LopesDivision of Bioinformatics and Biomedical Data Science, Federal University of São Paulo, São Paulo, Brazil.
Juliana PereiraSchool of Medicine, University of São Paulo, São Paulo, Brazil.
Luís Alberto P C LageSchool of Medicine, University of São Paulo, São Paulo, Brazil.
Igor B CostaEvandro Chagas Institute, Ananindeua, Brazil.
Camila M RomanoSchool of Medicine, University of São Paulo, São Paulo, Brazil.
Shirley V KomninakisSchool of Medicine, University of São Paulo, São Paulo, Brazil.
Jorge CassebSchool of Medicine, University of São Paulo, São Paulo, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Simian T-cell leukemia virus type 1 (STLV-1) and human T-lymphotropic virus type 1 (HTLV-1) are homologous viruses with high genetic identity. STLV-1 infections in non-human primates serve as valuable models to study HTLV-1 pathogenesis. Methods: This study investigated STLV-1 infection in captive green monkeys ( Results: STLV-1 infection was detected in seven animals, corresponding to a seroprevalence of 13.4%. Phylogenetic analysis showed that the STLV-1 strains identified are more closely related to baboon STLV-1 strains and human African HTLV-1 isolates than to other STLV-1 variants, suggesting a shared evolutionary history and possible cross-species transmission. Clinically and hematologically, STLV-1 infection in C. aethiops presented parallels to HTLV-1 infection in humans, including the presence of characteristic "flower cells" and similar lymphoproliferative disorders. Discussion: These findings reinforce the relevance of

Indexed as

adult T-cell leukemia/lymphomaATLLChlorocebus aethiopsHTLV-1STLV-1

Identifiers

PMID40662066
PMCPMC12256546

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.