Evidence map›Paper›PMID 40661935›Full record

ArticleERJ open research2025

Pandemic-disordered sleep: longer illness and more fatigue but little SARS-CoV-2 effect.

Simon Proctor, Nathan J Cheetham, Julia R B Brown, Vicky Bowyer, Barbara Toson, Nicholas R Harvey, Guy Leschziner, Desaline Joseph, Alexander Hammers, Carole H Sudre and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ERJ open research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Simon ProctorAdelaide Institute for Sleep Health/Flinders Health and Medical Research Institute, College of Medicine and Public Health, Flinders University, Bedford Park, SA, Australia.
Nathan J CheethamDepartment of Twin Research and Genetic Epidemiology, King's College London, London, UK.
Julia R B BrownDepartment of Twin Research and Genetic Epidemiology, King's College London, London, UK.
Vicky BowyerDepartment of Twin Research and Genetic Epidemiology, King's College London, London, UK.
Barbara TosonAdelaide Institute for Sleep Health/Flinders Health and Medical Research Institute, College of Medicine and Public Health, Flinders University, Bedford Park, SA, Australia.
Nicholas R HarveyDepartment of Twin Research and Genetic Epidemiology, King's College London, London, UK.
Guy LeschzinerSleep Disorders Centre and Department of Neurology, Guy's and St Thomas' NHS Foundation Trust, London, UK.
Desaline JosephDepartment of Paediatric Sleep Medicine, Evelina London Children's Health Care, Guy's and St Thomas' NHS Foundation Trust, London, UK.
Alexander HammersSchool of Biomedical Engineering and Imaging Sciences, King's College London, London, UK.
Carole H SudreSchool of Biomedical Engineering and Imaging Sciences, King's College London, London, UK.
COVID Symptom Study Biobank team
Claire J StevesDepartment of Twin Research and Genetic Epidemiology, King's College London, London, UK.
Sutapa MukherjeeAdelaide Institute for Sleep Health/Flinders Health and Medical Research Institute, College of Medicine and Public Health, Flinders University, Bedford Park, SA, Australia.
Emma L DuncanDepartment of Twin Research and Genetic Epidemiology, King's College London, London, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The COVID-19 pandemic disturbed sleep globally in both infected and uninfected individuals. Prolonged symptoms (particularly fatigue) after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection (post-COVID 2019 syndrome (PCS)) remain a health issue. Whether there is a relationship between PCS and sleep disturbance is largely unknown, with most studies lacking uninfected controls. We assessed sleep behaviours in a large UK cohort, analysing sleep disruption, fatigue, SARS-CoV-2 infection and symptom duration. Methods: UK adults previously recruited from the King's College London ZOE COVID Symptom Study to the COVID Symptom Study Biobank, with prospective symptom logging and SARS-CoV-2 testing, were invited to complete online validated questionnaires for sleep (Pittsburgh Sleep Quality Index, Sleep Condition Indicator, the STOP-Bang Questionnaire and Epworth Sleepiness Scale), fatigue (Chalder Fatigue Scale) and mental health (Generalised Anxiety Disorder 2 scale and Patient Health Questionnaire 2). Data were analysed considering SARS-CoV-2 infection, symptom duration and co-morbidities, including mental health. Results: Questionnaires were completed by 3833 of 8355 participants (2089 infected, 1721 uninfected, 23 unknown). Individuals with longer ( Conclusions: Sleep disturbance contributes to prolonged symptom reporting, irrespective of SARS-CoV-2 infection. Proven sleep interventions may help individuals with post-pandemic fatigue, including PCS.

Identifiers

PMID40661935
PMCPMC12257144

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.