Evidence map›Paper›PMID 40661824›Full record

ArticleCureus2025

Don't Bypass When There's Bilevel Positive Airway Pressure (BiPAP): Successful Management of Respiratory Distress and Atrial Flutter in a 77-Year-Old Woman Using BiPAP.

Angel U Davila-Cardona, Belissa A Lopez Pena, Ivan R Figueroa-Baez, Natalia Canevaro-Lugo, Juan A Ruiz Ramos

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Angel U Davila-CardonaInternal Medicine, San Juan City Hospital, San Juan, PRI.
Belissa A Lopez PenaInternal Medicine, San Juan City Hospital, San Juan, PRI.
Ivan R Figueroa-BaezInternal Medicine, San Juan City Hospital, San Juan, PRI.
Natalia Canevaro-LugoInternal Medicine, San Juan City Hospital, San Juan, PRI.
Juan A Ruiz RamosInternal Medicine, San Juan City Hospital, San Juan, PRI.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute decompensated heart failure (ADHF) often presents with respiratory distress and tachyarrhythmias such as atrial flutter, driven by autonomic dysregulation. Noninvasive ventilation, particularly bilevel positive airway pressure (BiPAP), can improve hemodynamic status and reduce respiratory effort. A 77-year-old woman with no prior cardiac history presented with acute shortness of breath, orthopnea, and paroxysmal nocturnal dyspnea. Examination of the ECG revealed atrial flutter with rapid ventricular response (HR: 144 bpm), hypoxemia (SpO₂: 89%), and pulmonary congestion. Imaging showed cardiomegaly and vascular redistribution; brain natriuretic peptide was elevated. She was initiated on BiPAP, resulting in rapid clinical improvement, including rate control and resolution of hypoxemia. This case demonstrates BiPAP's hemodynamic and autonomic benefits in ADHF. Evidence supports its role in reducing sympathetic overactivity, improving heart rate variability, and decreasing preload and afterload. Early BiPAP use may prevent intubation and improve outcomes in appropriately selected patients. Early initiation of BiPAP should be considered a cornerstone in the guideline-directed management of ADHF, particularly in patients with respiratory distress and atrial flutter.

Indexed as

acute decompensated heart failureatrial flutterautonomic dysregulationbipap noninvasive ventilationemergency managementhemodynamic stabilizationpulmonary edemarapid ventricular responsesinus rhythm conversion

Identifiers

PMID40661824
PMCPMC12258652

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.