Evidence map›Paper›PMID 40661763›Full record

ReviewFrontiers in plant science2025

Exploiting microalgal diversity for sterol production.

Omnia H Abdelkarim, Rene H Wijffels, Maria J Barbosa

Abstract readReview
In one paragraph

Review in Frontiers in plant science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Omnia H AbdelkarimBioprocess Engineering, AlgaePARC, Wageningen University, Wageningen, Netherlands.
Rene H WijffelsBioprocess Engineering, AlgaePARC, Wageningen University, Wageningen, Netherlands.
Maria J BarbosaBioprocess Engineering, AlgaePARC, Wageningen University, Wageningen, Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sterols are essential for eukaryotic cell membrane integrity and fluidity, and they demonstrate valuable pharmaceutical and nutraceutical benefits, including anti-inflammatory, antioxidant, anti-cancer, and cholesterol-lowering properties. Traditionally, animal, plant, and microbial fermentation sterols face sustainability, economic, and ethical challenges. Microalgae have emerged as a promising alternative due to their biochemical diversity, rapid growth, and controlled cultivation capabilities. This review explores microalgae's potential for sterol production, highlighting their advantages, including sustainability and sterol profile diversity, while addressing key challenges of low sterol yields, species-dependent variations, and industrial scalability. We discuss how recent advancements in metabolic engineering, cultivation technologies, and process optimization could enhance sterol production. By integrating innovative biotechnological strategies, microalgae hold the potential to become a viable and sustainable sterol source for pharmaceutical, nutraceutical, and industrial applications.

Indexed as

biotechnological applicationenvironmental conditionsgenetic engineeringmicroalgaesterols production

Identifiers

PMID40661763
PMCPMC12256458

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.