Evidence map›Paper›PMID 40661690›Full record

ArticleFrontiers in nutrition2025

Association of non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol (NHHR) and sarcopenia in elderly adults.

Yi Lin, Xiaocong Shi, Weijia Wu, Xiyi Chen

Abstract read
In one paragraph

Article in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yi LinDepartment of Endocrinology, The Third Affiliated Hospital of Shanghai University, Wenzhou People's Hospital, Wenzhou, China.
Xiaocong ShiDepartment of Endocrinology, The Third Affiliated Hospital of Shanghai University, Wenzhou People's Hospital, Wenzhou, China.
Weijia WuDepartment of Cardiovascular and Thoracic Surgery, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.
Xiyi ChenDepartment of Cardiovascular and Thoracic Surgery, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: This study aimed to explore the link between non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio (NHHR) and sarcopenia in elderly adults using data from the National Health and Nutrition Examination Survey (NHANES). Methods: The dataset from NHANES 1999-2004. Different statistical analyses, including logistic regression, restricted cubic spline, two-piecewise linear regression, subgroup analyses, and interaction tests models, were used to examine the relationship between NHHR and the risk of sarcopenia. Results: Total 3,190 elderly participants were included and 676 (21.2%) of them had sarcopenia. In crude model, the odds ratio (OR) of NHHR on sarcopenia was 0.71 [95% confidence interval (CI), 0.66-0.77]. After adjusting for all factors, the ORs for NHHR tertiles 2 and 3 were 0.76 (95% CI: 0.58-0.99) and 0.70 (95% CI: 0.53-0.94), respectively, with a significant trend ( Conclusion: We found that NHHR was negatively associated with risk of sarcopenia in elderly adults.

Indexed as

elderlylipidsNHANESNHHRsarcopenia

Identifiers

PMID40661690
PMCPMC12256216

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.