Evidence map›Paper›PMID 40661571›Full record

ArticlebioRxiv : the preprint server for biology2025

Non-inertial scan angle multiplier for expanded fields-of-view.

Che-Hang Yu, Yiyi Yu, Joseph S Canzano, Yuandong Fei, Spencer LaVere Smith

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Che-Hang YuDepartment of Electrical and Computer Engineering, University of California Santa Barbara, 2002, BioEngineering Building, Santa Barbara, CA 93106-5100, USA.ORCID 0000-0002-0353-9752
Yiyi YuDepartment of Electrical and Computer Engineering, University of California Santa Barbara, 2002, BioEngineering Building, Santa Barbara, CA 93106-5100, USA.ORCID 0000-0003-1053-413X
Joseph S CanzanoDepartment of Electrical and Computer Engineering, University of California Santa Barbara, 2002, BioEngineering Building, Santa Barbara, CA 93106-5100, USA.ORCID 0000-0002-5371-4846
Yuandong FeiDepartment of Electrical and Computer Engineering, University of California Santa Barbara, 2002, BioEngineering Building, Santa Barbara, CA 93106-5100, USA.
Spencer LaVere SmithDepartment of Electrical and Computer Engineering, University of California Santa Barbara, 2002, BioEngineering Building, Santa Barbara, CA 93106-5100, USA.

Funding

Cortical visual processing for navigationR01NS121919 · NINDS · UNIVERSITY OF CALIFORNIA SANTA BARBARA · PI GOARD, MICHAEL, NIELL, CRISTOPHER M · 2024 to 2025
$1.9M
Visual representations across cortical areasR01EY035378 · NEI · UNIVERSITY OF CALIFORNIA SANTA BARBARA · PI SPENCER LAVERE SMITH · 2023 to 2026
$1.6M
Advanced optics to unlock large field-of-view multiphoton imaging for neuroscience and beyondR41MH136563 · NIMH · PACIFIC OPTICA, INC. · PI SMITH, SPENCER LAVERE · 2023 to 2024
$581k
Unlocking the potential of High-speed widefield ImagingR21EY034291 · NEI · UNIVERSITY OF CALIFORNIA SANTA BARBARA · PI THEOGARAJAN, LUKE SATISH KUMAR · 2022 to 2024
$566k
NEI NIH HHS R01 EY035378NEI NIH HHS R21 EY034291NIMH NIH HHS R41 MH136563NINDS NIH HHS R01 NS121919
6 · The paper itself

Abstract

In many laser scan engines, mechanical inertia imposes a tradeoff between mirror diameter (mass) and scan speed (cycle time) and/or scan angle amplitude. Ultimately, this limits the field-of-view and/or scan speed in multiphoton and confocal imaging, laser-based manufacturing, and other applications. To push parameters past this inertia limit, we present a non-inertial (stationary) add-on unit that doubles the scan angle amplitude while preserving both the beam size and cycle time, thus doubling the étendue (optical invariant) and overall system throughput. We demonstrate its use in two-photon calcium imaging of neural activity in living mice. We also adapt the approach to present a phase doubling unit that doubles the maximum range of phase modulators. Finally, we describe further variants including generalizing the approach to Nx scan angle multiplication (N = 2, 3, 4, ...) with diffraction limited performance across a wide scan angle range and over a broad wavelength bandwidth. These non-inertial scan angle multipliers (called Nisam2x, 3x, ...) can expand the capabilities of a range of technologies including imaging, adaptive optics, sensing, marking, and manufacturing.

Identifiers

PMID40661571
PMCPMC12259198

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.